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Metronidazole Topical Dosage

Applies to the following strength(s): 1% ; 0.75% ; 0.75% with cleanser ; 1.3%

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Acne Rosacea

1% Topical Cream or Gel: Apply and rub in a thin film to the affected area(s) once a day

0.75% Topical Cream, Gel, or Lotion: Apply and rub in a thin layer to affected area(s) twice a day in the morning and evening

Comments:
-A gentle cleaner should be used prior to application.
-Cosmetics may be applied following application.

Use: For the topical treatment of inflammatory lesions and erythema of rosacea

Usual Adult Dose for Bacterial Vaginosis

1.3% Vaginal Gel: Insert 1 applicatorful intravaginally once at bedtime

0.75% Vaginal Gel: Insert 1 applicatorful intravaginally once or twice a day for 5 days; once a day dosing should be administered at bedtime

Use: For the treatment of bacterial vaginosis in non-pregnant women

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Mild to moderate liver dysfunction: Data not available
Severe liver dysfunction: Use with caution.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Topical 0.75% and 1% formulations: For topical use only; not for oral, ophthalmic, or intravaginal use.
-Vaginal 0.75% and 1.3% formulations: For intravaginal use only; not for ophthalmic, dermal, or oral use.

Storage requirements:
-Vaginal gel: Protect from freezing; do not refrigerate; protect from extreme heat.

Patient advice:
-A gentle cleanser should be used prior to application of topical products for rosacea; cosmetics may be applied following application.
-Avoid use of alcohol during therapy and for at least 24 hours (1.3% gel) or 3 days after discontinuing treatment.
-Avoid sexual intercourse and use of other vaginal products (e.g., tampons or douches) following the single administration of the vaginal gel.
-Discontinue use and contact your physician if vaginal irritation occurs.
-Consult the Patient Instructions for Use for proper administration techniques.

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