Generic Name: metronidazole vaginal (MET roe NYE da zole)
Brand Name: MetroGel-Vaginal, Nuvessa, Vandazole
What is metronidazole vaginal?
Metronidazole is an antibiotic that fights bacteria in the body.
Metronidazole vaginal (for use in the vagina) is used to treat vaginal infections caused by bacteria.
Metronidazole vaginal may also be used for purposes not listed in this medication guide.
What is the most important information I should know about metronidazole vaginal?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before using metronidazole vaginal?
You should not use this medicine if you are allergic to metronidazole, or if:
you are allergic to parabens or polyethylene glycol;
you recently drank alcohol; or
you took disulfiram (Antabuse) within the past 14 days.
To make sure metronidazole vaginal is safe for you, tell your doctor if you have:
a seizure disorder;
a blood cell disorder (such as anemia, or low platelets); or
peripheral vascular disease such as Raynaud's syndrome.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
Metronidazole vaginal can pass into breast milk and may harm a nursing baby. Do not breast-feed within 24 hours after using this medicine. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
Metronidazole vaginal is not approved for use by anyone younger than 18 years old.
How should I use metronidazole vaginal?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Use this medicine at bedtime.
Metronidazole vaginal is often given as a single dose. However, you might need to use the medicine for 5 nights in a row. Follow your doctor's dosing instructions very carefully.
Do not take metronidazole vaginal by mouth. It is for use only in the vagina.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Gently wash your vaginal area before applying the medicine. Wash your hands before and after handling the medicine tube or vaginal applicator.
Insert the medicine directly into your vagina using the applicator provided.
The single-use applicator is for one use only. Throw the applicator away after one use, even if there is still some medicine left in it after inserting your dose.
If your medicine comes with only one plastic applicator, wash and rinse the applicator after each use. Throw away the applicator after you are finished using this medicine.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics.
You may need to use a sanitary napkin during treatment, but do not use a tampon. Do not use a douche or other vaginal product while using metronidazole vaginal.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using metronidazole vaginal.
Call your doctor if your symptoms do not improve, or if they get worse.
Metronidazole vaginal will not treat a vaginal yeast infection. You may even develop a new vaginal yeast infection after using this medicine. Watch for symptoms such as itching or discharge during or after treatment with metronidazole vaginal.
Store at room temperature away from moisture or heat. Do not allow the medicine to freeze.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
An overdose of metronidazole vaginal is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
What should I avoid while using metronidazole vaginal?
While you are using this medicine and for 24 hours after your last dose: Avoid drinking alcohol or consuming foods or other products that contain alcohol or propylene glycol. Check the ingredient label of all foods and beverages you consume.
Avoid wearing tight-fitting, synthetic clothing such as nylon underwear or panty hose that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.
Avoid getting this medicine in your eyes, nose, or mouth. Rinse with water if this medicine gets into any of these areas.
Avoid having sex until your vaginal infection has been completely treated.
Metronidazole vaginal side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Rare but serious side effects may include:
seizure (convulsions); or
numbness, burning, pain, or tingly feeling in your hands or feet.
Call your doctor at once if you have new or worsening vaginal symptoms.
Common side effects may include:
vaginal itching or discharge;
nausea, diarrhea; or
cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Metronidazole vaginal dosing information
Usual Adult Dose for Acne Rosacea:
1% Topical Cream or Gel: Apply and rub in a thin film to the affected area(s) once a day
0.75% Topical Cream, Gel, or Lotion: Apply and rub in a thin layer to affected area(s) twice a day in the morning and evening
-A gentle cleaner should be used prior to application.
-Cosmetics may be applied following application.
Use: For the topical treatment of inflammatory lesions and erythema of rosacea
Usual Adult Dose for Bacterial Vaginosis:
1.3% Vaginal Gel: Insert 1 applicatorful intravaginally once at bedtime
0.75% Vaginal Gel: Insert 1 applicatorful intravaginally once or twice a day for 5 days; once a day dosing should be administered at bedtime
Use: For the treatment of bacterial vaginosis in non-pregnant women
What other drugs will affect metronidazole vaginal?
Tell your doctor about all your current medicines and any you start or stop using, especially:
a blood thinner (warfarin, Coumadin, Jantoven).
This list is not complete. Other drugs may interact with metronidazole vaginal, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about metronidazole topical
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- 96 Reviews – Add your own review/rating
- Drug class: topical anti-rosacea agents
- Metronidazole cream
- Metronidazole emulsion
- Metronidazole gel
- Metronidazole topical
- Metronidazole Topical (Advanced Reading)
- Metronidazole Vaginal (Advanced Reading)
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about metronidazole vaginal.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 6.01.
Last reviewed: December 11, 2015
Date modified: July 02, 2017