Comparing Cymbalta vs Fluoxetine
| Cymbalta Remove Cymbalta from your drug comparison | Fluoxetine Remove Fluoxetine from your drug comparison |
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| Cymbalta duloxetine Remove Cymbalta from your drug comparison | Fluoxetine Remove Fluoxetine from your drug comparison | ||||||||||||||||
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Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Fluoxetine may be used for the treatment of depression and other mood disorders. It is more likely to cause insomnia than drowsiness. Prescribed for Anxiety and Stress, Major Depressive Disorder... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea, sedated state, headache, and xerostomia. See the full Cymbalta side effects document. |
See the full fluoxetine side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Cymbalta prices and generic prices |
View all fluoxetine prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Other duloxetine brands include: Drizalma Sprinkle, Irenka | Prozac | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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17 hours |
210 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 565 drugs are known to interact with Cymbalta:
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A total of 637 drugs are known to interact with fluoxetine:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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N/A |
December 29, 1987 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.