Cold & Hot Pain Relief Alternatives Compared
| Cold & Hot Pain Relief (methyl salicylate) | Humira (adalimumab) | Methotrexate |
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| Cold & Hot Pain Relief (methyl salicylate) | Humira (adalimumab) | Methotrexate |
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Prescription and OTC
Prescribed for Osteoarthritis, Muscle Pain, Rheumatoid Arthritis. Cold & Hot Pain Relief may also be used for purposes not listed in this medication guide. |
Prescription only
Humira is a TNF-alfa inhibitor that may be used to treat a wide range of different inflammatory conditions, such as Rheumatoid Arthritis, psoriasis, ankylosing spondylitis, Crohn's disease, and... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis, rheumatoid arthritis, polyarticular juvenile idiopathic arthritis (pJIA), mycosis fungoides, and certain cancers, such as ALL or... View more |
Related suggestions Rheumatoid Arthritis
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| More about (methyl salicylate) | More about Humira (adalimumab) | More about Methotrexate | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Be the first to share your experience with this drug. |
Humira has an average rating of 6.4 out of 10 from a total of 702 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 30% reported a negative effect. |
Methotrexate has an average rating of 6.5 out of 10 from a total of 337 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
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View all Cold & Hot Pain Relief side effects |
View all Humira side effects |
View all Methotrexate side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Humira prices |
View all Methotrexate prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Other methyl salicylate brands include: Aloe Vera Liniment, Analgesic Balm, Analgesic Balm Greaseless, Arthricare Cream, Banalg, Banalg Hospital Strength, Boroleum, Castiva Cooling, Cooling Gel, Deep Down Pain Relief, Duraflex Comfort, Eucalyptamint, Exocaine Plus, Flex-All 454, Flex-All 454 Maximum Strength, Flex-All 454 Ultra Plus, Gordogesic, Heet Triple Action, Menthol C, Mentholatum Deep Heating, Mentholatum Ointment, Mentholatum Pain Gel, Mentholatum Pain Patch, Minit Rub, Pain Stick Arthritis Formula, Pain Stick Sports Formula, PainZone, Salonpas Pain Gel, Salonpas Pain Patch, Salonpas Pain Spray, Satogesic, Satogesic Hot Gel, Satogesic Pad, Therapeutic Pain Relief View more | Other adalimumab brands include: Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Hyrimoz, Idacio, Simlandi, Yuflyma, Yusimry View more | Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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N/A |
480 hours |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 8 drugs are known to interact with Cold & Hot Pain Relief:
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A total of 553 drugs are known to interact with Humira:
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A total of 726 drugs are known to interact with Methotrexate:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||
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N/A |
December 31, 2002 |
December 07, 1953 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
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N/A |
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| Professional Resources | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.