Ciprofloxacin Alternatives Compared
| Ciprofloxacin | Nitrofurantoin | Macrobid |
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| Ciprofloxacin | Nitrofurantoin | Macrobid nitrofurantoin |
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Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, it should not be given to children aged less than 18 and in adults, it should be reserved for infections... View more |
Nitrofurantoin is an effective antibiotic with a low risk of inducing bacterial resistance that is used specifically to treat urinary tract infections caused by susceptible bacteria. Long-term use... View more |
Prescribed for Urinary Tract Infection, Prevention of Bladder infection, Bladder Infection. Macrobid may also be used for purposes not listed in this medication guide. |
Choose a suggestion below Urinary Tract Infection
Bladder Infection
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| More about Ciprofloxacin | More about Nitrofurantoin | More about Macrobid (nitrofurantoin) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Ciprofloxacin has an average rating of 5.0 out of 10 from a total of 862 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 47% reported a negative effect. |
Nitrofurantoin has an average rating of 4.3 out of 10 from a total of 1729 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 53% reported a negative effect. |
Macrobid has an average rating of 4.5 out of 10 from a total of 771 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 51% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: pyelonephritis, arthralgia, musculoskeletal signs and symptoms. See the full ciprofloxacin side effects document. |
See the full nitrofurantoin side effects document. |
See the full Macrobid side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all ciprofloxacin prices |
View all nitrofurantoin prices |
View all Macrobid prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR | Furadantin, Macrobid, Macrodantin | Other nitrofurantoin brands include: Furadantin, Macrodantin | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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4 hours |
1 hour |
1 hour |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 622 drugs are known to interact with ciprofloxacin:
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A total of 178 drugs are known to interact with nitrofurantoin:
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A total of 178 drugs are known to interact with Macrobid:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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October 22, 1987 |
February 06, 1953 |
December 24, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
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N/A |
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.