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Comparing Ceftriaxone vs Ciprofloxacin

Ceftriaxone

Ciprofloxacin

Prescribed for Urinary Tract Infection, Bacterial Infection, Bone infection, Bacteremia, Bacterial Endocarditis Prevention, Bronchitis, Salmonella Gastroenteritis, Pelvic Inflammatory Disease,... more

Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, its use is restricted in children and it carries a risk of tendinitis or tendon rupture. Prescribed for... more

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Urinary Tract Infection
Bacterial Infection
Bronchitis
Pneumonia
Skin or Soft Tissue Infection
Kidney Infections (Pyelonephritis)
Prostatitis
Skin and Structure Infection
Bone infection (Osteomyelitis)
Surgical Prophylaxis
Peritonitis
Gonococcal Infection, Uncomplicated
Intraabdominal Infection
Salmonella Gastroenteritis
Epididymitis, Sexually Transmitted
Typhoid Fever
Bacteremia
Joint Infection
Gonococcal Infection, Disseminated
Meningococcal Meningitis Prophylaxis
Shigellosis
Salmonella Enteric Fever
Chancroid
Show more conditions...

Prescription only

Prescription only

Ratings & Reviews

Recent helpful reviews
8.5
89 Reviews

For Urinary Tract Infection Received a one time shot (somewhat painful), and was feeling better inside of an hour.

10
Cindy2K
5.6
597 Reviews

For Urinary Tract Infection I was placed on this antibiotic because Bactrim gives me nasty side effects and I told my doctor that so she gave me this. Never been on this for a UTI before and I’ve had a UTI every 4 months almost ON THE DOT for the past 2 years. Literally have been to urgent care 4/3, was just back there on 9/3. so about every 4-5 months I’m back there. Anyway, she put me on this one and so far the only major side effect is that I’ve had trouble sleeping and my feet get really dry. ALSO THE WORST ONE is that urgency to pee is just hanging around, like I still have a UTI or something, and I’m on day 4 out of 5 of treatment. Just hoping this awfulness ends soon. I bought AZO urgency pain relief pills and those always help.

5
allltheproblems

For Urinary Tract Infection No huge side effects yet. Just took third dose. I already have anxiety so that side effect I can deal with. Hoping my UTI will start clearing up soon. This is my first time taking this drug. I will comment back with results and updates in a few days. 30 year old male.

5
Bill0987

View all 89 reviews

View all 597 reviews

Drug Class

Side Effects

See the full ceftriaxone side effects document.

Commonly reported side effects include: pyelonephritis, arthralgia, and musculoskeletal signs and symptoms.

See the full ciprofloxacin side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 1 powder for injection
Dosage 1 g
Per Unit* $39.63 - $41.44
Cost* $39.63 - $41.44
View all ceftriaxone prices
Quantity 1 tablet
Dosage 500 mg
Per Unit* $9.28
Cost* $9.28
View all ciprofloxacin prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Injectable powder for injection
  • Intravenous powder for injection
  • Intravenous solution
  • Intravenous solution
  • Oral powder for reconstitution
  • Oral tablet
  • Oral tablet, extended release

Brand Names

N/A

 Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR, and Proquin XR

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

8 hours

4 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (6)

Drug Interactions

A total of 61 drugs are known to interact with ceftriaxone:

  • 10 major drug interactions (51 brand and generic names)
  • 45 moderate drug interactions (469 brand and generic names)
  • 6 minor drug interactions (24 brand and generic names)

A total of 857 drugs are known to interact with ciprofloxacin:

  • 149 major drug interactions (923 brand and generic names)
  • 618 moderate drug interactions (3880 brand and generic names)
  • 90 minor drug interactions (258 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No results found - however, this does not necessarily mean no warnings exist. Always consult with your doctor or pharmacist.
  • Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified... more

Disease Interactions

First Approval Date

December 21, 1984

October 22, 1987

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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