Comparing Amoxicillin vs Ciprofloxacin

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Amoxicillin

Ciprofloxacin

Amoxicillin is a penicillin-type antibiotic that only treats infections caused by susceptible bacteria. It is usually well tolerated. Prescribed for Bacterial Infection, Bacterial Endocarditis... View more

Ciprofloxacin is an effective antibiotic that treats a wide variety of infections; however, it should not be given to children aged less than 18 and in adults, it should be reserved for infections... View more

Prescription only

Commonly reported side effects include: pyelonephritis, arthralgia, and musculoskeletal signs and symptoms.

See the full ciprofloxacin side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	4 capsule
Dosage	500 mg
Per Unit^*	$2.51
Cost^*	$10.02

View all amoxicillin prices

Quantity	1 tablet
Dosage	500 mg
Per Unit^*	$11.09
Cost^*	$11.09

View all ciprofloxacin prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral capsule
Oral powder for reconstitution
Oral tablet
Oral tablet, chewable
Oral tablet, extended release

Intravenous solution
Oral powder for reconstitution
Oral tablet
Oral tablet, extended release

Brand Names

Amoxil, Apo-Amoxi Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

1.7 hours

4 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 37 drugs are known to interact with amoxicillin:

4 major drug interactions (17 brand and generic names)
25 moderate drug interactions (209 brand and generic names)
8 minor drug interactions (39 brand and generic names)

A total of 603 drugs are known to interact with ciprofloxacin:

145 major drug interactions (616 brand and generic names)
377 moderate drug interactions (2702 brand and generic names)
81 minor drug interactions (227 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified... View more

Disease Interactions

First Approval Date

January 18, 1974

October 22, 1987

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer