Comparing Chlorpheniramine vs Hydroxyzine
| Chlorpheniramine | Hydroxyzine |
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| Chlorpheniramine | Hydroxyzine |
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Prescription and OTC
Prescribed for Urticaria, Allergic Reactions, Allergic Rhinitis, Cold Symptoms, Allergies, Food Allergies. Chlorpheniramine may also be used for purposes not listed in this medication guide. |
Prescription only
Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more |
Related suggestions Allergies
Food Allergies
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| More about Chlorpheniramine | More about Hydroxyzine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Chlorpheniramine has an average rating of 8.2 out of 10 from a total of 53 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 13% reported a negative effect. |
Hydroxyzine has an average rating of 5.9 out of 10 from a total of 1407 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Chlorpheniramine side effects |
View all Hydroxyzine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Chlorpheniramine prices |
View all Hydroxyzine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aller-Chlor, Allergy Relief, Allergy Time, C.P.M., Chlo-Amine, Chlor-Mal, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, Chlorphen, Chlorpheniramine (Allergy), ChlorTan, Ed Chlor Ped Jr., Ed Chlor-Tan, Ed ChlorPed, Ed-Chlortan, Ricobid H, Teldrin HBP Allergy, Topco Allergy, Wal-finate View more | Vistaril | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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30 hours |
7 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 344 drugs are known to interact with Chlorpheniramine:
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A total of 581 drugs are known to interact with Hydroxyzine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 13, 1949 |
April 12, 1956 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.