Comparing Chlorpheniramine vs Hydroxyzine
| Chlorpheniramine | Hydroxyzine |
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| Chlorpheniramine | Hydroxyzine |
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Prescription and OTC
Prescribed for Urticaria, Allergic Reactions, Allergic Rhinitis, Cold Symptoms, Allergies, Food Allergies. Chlorpheniramine may also be used for purposes not listed in this medication guide. |
Prescription only
Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more |
Related suggestions Allergies
Food Allergies
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| More about Chlorpheniramine | More about Hydroxyzine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Chlorpheniramine has an average rating of 8.2 out of 10 from a total of 53 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 13% reported a negative effect. |
Hydroxyzine has an average rating of 5.9 out of 10 from a total of 1404 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Chlorpheniramine side effects |
View all Hydroxyzine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Chlorpheniramine prices |
View all Hydroxyzine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aller-Chlor, Allergy Relief, Allergy Time, C.P.M., Chlo-Amine, Chlor-Mal, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, Chlorphen, Chlorpheniramine (Allergy), ChlorTan, Ed Chlor Ped Jr., Ed Chlor-Tan, Ed ChlorPed, Ed-Chlortan, Ricobid H, Teldrin HBP Allergy, Topco Allergy, Wal-finate View more | Vistaril | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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30 hours |
7 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 344 drugs are known to interact with Chlorpheniramine:
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A total of 581 drugs are known to interact with Hydroxyzine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 13, 1949 |
April 12, 1956 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.