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Chlorpheniramine Pregnancy and Breastfeeding Warnings

Chlorpheniramine is also known as: Aller-Chlor, Allergy Relief, Allergy Time, C.P.M., Chlo-Amine, Chlor-Mal, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, ChlorTan, Chlorphen, Chlorpheniramine (Allergy), Ed Chlor Ped Jr., Ed Chlor-Tan, Ed ChlorPed, Ed-Chlortan, P-Tann, PediaTan, Pharbechlor, Ricobid H, TanaHist-PD, Teldrin HBP Allergy, Topco Allergy, Wal-finate

Chlorpheniramine Pregnancy Warnings

The Collaborative Perinatal Project monitored 1,070 first trimester exposures and 3,931 exposures which occurred anytime during pregnancy. No evidence was found to suggest a relationship to large categories of malformations. Antihistamine exposure in the first trimester in general was not associated with an increased risk of malformations.

Chlorpheniramine has been assigned to pregnancy category B by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Chlorpheniramine is only recommended for use during pregnancy when benefit outweighs risk.

See references

Chlorpheniramine Breastfeeding Warnings

There are no data on the excretion of chlorpheniramine into human milk. However, because other antihistamines are excreted into human milk in low concentrations, the manufacturer recommends that caution be used when administering chlorpheniramine to nursing women.

See references

References for pregnancy information

  1. "Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
  2. Black RA, Hill DA "Over-the-counter medications in pregnancy." Am Fam Physician 67 (2003): 2517-24
  3. Heinonen O, Slone D, Shapiro S; Kaufman DW ed. "Birth Defects and Drugs in Pregnancy." Littleton, MA: Publishing Sciences Group, Inc. (1977): 297
  4. Nelson MA, Forfar JO "Associations between drugs administered during pregnancy and congenital abnormalities of the fetus." Br Med J 1 (1971): 523-7

References for breastfeeding information

  1. "Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.

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