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Chlorpheniramine Pregnancy and Breastfeeding Warnings

Chlorpheniramine is also known as: Aller-Chlor, Allergy Relief, Allergy Time, C.P.M., Chlo-Amine, Chlor-Mal, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, ChlorTan, Chlorphen, Chlorpheniramine (Allergy), Ed Chlor Ped Jr., Ed Chlor-Tan, Ed ChlorPed, Ed-Chlortan, P-Tann, PediaTan, Pharbechlor, Ricobid H, TanaHist-PD, Teldrin HBP Allergy, Topco Allergy, Wal-finate

Medically reviewed by Drugs.com. Last updated on Apr 13, 2020.

Chlorpheniramine Pregnancy Warnings

Animal studies are not available. There are no controlled data in human pregnancy. The Collaborative Perinatal Project monitored 1070 mother-child pairs with first trimester exposure to this drug and 3931 any time pregnancy exposures, neither of which suggested a relationship to minor or major malformations, possible associations which require independent confirmation include polydactyly, gastrointestinal defects, eye and ear defects, hydrocephaly, congenital dislocation of the hip, and malformations of the female genitalia. The background birth defect and miscarriage risk for the indicated population is not known.

AU TGA pregnancy category A: Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed.

US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D, and X are being phased out.

Use is not recommended.

AU TGA pregnancy category: A
US FDA pregnancy category: Not assigned

Comments:
-Third trimester use may cause reactions in the newborn or premature neonates.

See references

Chlorpheniramine Breastfeeding Warnings

Use is not recommended.

Excreted into human milk: Data not available
Excreted into animal milk: Data not available

Comments:
-Antihistamines may inhibit lactation and small amounts may be secreted in breast milk.

See references

References for pregnancy information

  1. Briggs GG, Freeman RK. "Drugs in Pregnancy and Lactation. 10th ed." Philadelphia, PA: Wolters Kluwer Health (2015):
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. TGA. Therapeutic Goods Administration. Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. Available from: URL: http://www.tga.gov.au/docs/html/medpreg.htm." ([1999]):

References for breastfeeding information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.