Comparing Amitriptyline vs Olanzapine
| Amitriptyline | Olanzapine |
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| Amitriptyline | Olanzapine |
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Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Prescription only
Olanzapine is an oral antipsychotic that may be used to treat schizophrenia or bipolar disorder. Weight gain is common in people who take olanzapine. Prescribed for Major Depressive Disorder... View more |
Related suggestions Depression
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| More about Amitriptyline | More about Olanzapine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amitriptyline has an average rating of 7.6 out of 10 from a total of 1808 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
Olanzapine has an average rating of 5.9 out of 10 from a total of 1096 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Amitriptyline side effects |
View all Olanzapine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amitriptyline prices |
View all Olanzapine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Zyprexa, Zyprexa Intramuscular, Zyprexa Relprevv, Zyprexa Zydis | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
54 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 717 drugs are known to interact with Amitriptyline:
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A total of 666 drugs are known to interact with Olanzapine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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April 07, 1961 |
September 30, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.