Comparing Amitiza vs Relistor
| Amitiza | Relistor |
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| Amitiza (lubiprostone) | Relistor (methylnaltrexone) |
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Prescription only
Prescribed for Chronic Idiopathic Constipation, Opioid-Induced Constipation, Irritable Bowel Syndrome with Constipation. Amitiza may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Constipation - Chronic, Constipation - Drug Induced, Opioid-Induced Constipation. Relistor may also be used for purposes not listed in this medication guide. |
Related suggestions Opioid-Induced Constipation
Popular comparisons
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| More about Amitiza (lubiprostone) | More about Relistor (methylnaltrexone) | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Amitiza has an average rating of 5.6 out of 10 from a total of 271 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 39% reported a negative effect. |
Relistor has an average rating of 6.3 out of 10 from a total of 57 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include:
See also: Amitiza side effects in more detail. |
See also: Relistor side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Amitiza prices and generic prices |
View all Relistor prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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N/A |
8 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 1 drugs are known to interact with Amitiza:
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A total of 18 drugs are known to interact with Relistor:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 31, 2006 |
April 24, 2008 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
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N/A |
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| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.