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Medications for Constipation, Chronic

What is Constipation, Chronic:  Chronic Constipation is a long term condition in which bowel movements are infrequent or incomplete.

Medications to treat Constipation, Chronic

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Linzess Rx C N 242 reviews
7.0

Generic name: linaclotide systemic

Drug class: guanylate cyclase-C agonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Amitiza Rx C N 109 reviews
6.0

Generic name: lubiprostone systemic

Drug class: chloride channel activators

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
lactulose Rx B N 24 reviews
9.0

Generic name: lactulose systemic

Brand names:  Generlac, Enulose, Constulose, Kristalose

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Generlac Rx B N 2 reviews
9.0

Generic name: lactulose systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Enulose Rx B N Add review
10

Generic name: lactulose systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Relistor Rx B N 2 reviews
4.0

Generic name: methylnaltrexone systemic

Drug class: peripheral opioid receptor antagonists

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
GoLYTELY Rx C N 3 reviews
9.0

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Constulose Rx B N 1 review
10

Generic name: lactulose systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
polyethylene glycol 3350 with electrolytes Rx C N 10 reviews
8.0

Generic name: polyethylene glycol 3350 with electrolytes systemic

Brand names:  GoLYTELY, MoviPrep, PEG-3350 with Electolytes, GaviLyte-N, Colyte, Suclear, TriLyte, GaviLyte-C, GaviLyte-G, NuLYTELY

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
Kristalose Rx B N Add review Add

Generic name: lactulose systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
colchicine Off Label Rx C N Add review Add

Generic name: colchicine systemic

Drug class: antigout agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
linaclotide Rx C N 247 reviews
7.0

Generic name: linaclotide systemic

Brand name:  Linzess

Drug class: guanylate cyclase-C agonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

 
MoviPrep Rx C N 3 reviews
7.0

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
lubiprostone Rx C N 111 reviews
6.0

Generic name: lubiprostone systemic

Brand name:  Amitiza

Drug class: chloride channel activators

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
PEG-3350 with Electolytes Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

 
GaviLyte-N Rx C N 1 review
10

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
methylnaltrexone Rx B N 2 reviews
4.0

Generic name: methylnaltrexone systemic

Brand name:  Relistor

Drug class: peripheral opioid receptor antagonists

For consumers: dosage, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Colyte Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Movantik Rx C N 3 reviews
1.0

Generic name: naloxegol systemic

Drug class: peripheral opioid receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Suclear Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
TriLyte Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
GaviLyte-C Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
GaviLyte-G Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
naloxegol Rx C N 3 reviews
1.0

Generic name: naloxegol systemic

Brand name:  Movantik

Drug class: peripheral opioid receptor antagonists

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
NuLYTELY Rx C N Add review Add

Generic name: polyethylene glycol 3350 with electrolytes systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 

Alternative treatments for Constipation, Chronic

The following products are considered to be alternative treatments or natural remedies for Constipation, Chronic. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Constipation, Chronic.

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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