Skip to Content

NuLYTELY Side Effects

Generic Name: polyethylene glycol 3350 with electrolytes

Note: This document contains side effect information about polyethylene glycol 3350 with electrolytes. Some of the dosage forms listed on this page may not apply to the brand name NuLYTELY.

For the Consumer

Applies to polyethylene glycol 3350 with electrolytes: oral powder for solution

Along with its needed effects, polyethylene glycol 3350 with electrolytes (the active ingredient contained in NuLYTELY) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking polyethylene glycol 3350 with electrolytes:

Rare

  • Cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin
  • shortness of breath
  • skin rash, hives or welts, or itching
  • tightness in the chest
  • unusual tiredness or weakness

Incidence Not Known

  • Bloody or black, tarry stools
  • blue lips and fingernails
  • chest pain
  • constipation
  • coughing that sometimes produces a pink frothy sputum
  • difficult or labored breathing (sudden)
  • difficult, fast, or noisy breathing, sometimes with wheezing
  • increased sweating
  • pale skin
  • severe stomach pain
  • swelling in the legs and ankles
  • tightness in the chest (sudden)
  • vomiting
  • vomiting of blood or material that looks like coffee grounds

Some side effects of polyethylene glycol 3350 with electrolytes may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

Less Common

  • Abdominal or stomach cramps
  • burning or itching around the anus

Rare

  • Blistering, crusting, irritation, itching, or reddening of the skin
  • cracked, dry, or scaly skin
  • runny nose
  • swelling

For Healthcare Professionals

Applies to polyethylene glycol 3350 with electrolytes: oral kit, oral powder for reconstitution

General

The most common adverse events were abdominal distension, anal discomfort, thirst, nausea, and abdominal pain. Since diarrhea is considered part of the efficacy of this product, it was not defined as an adverse reaction.[Ref]

Gastrointestinal

Very common (10% or more): Abdominal distension (59.8%), anal discomfort (52%), nausea (47.3%), abdominal pain (39.1%), vomiting (12.8%)

Common (1% to 10%): Upper abdominal pain, dyspepsia

Frequency not reported: Upper gastrointestinal bleeding from a Mallory-Weiss tear, esophageal perforation, borborygmi, flatulence[Ref]

Metabolic

Very common (10% or more): Hunger (70.8%)

Common (1% to 10%): Hypokalemia, hyperphosphatemia

Frequency not reported: Electrolyte disturbances, hyperkalemia[Ref]

Other

Very common (10% or more): Rigors (33.7%), malaise (26.6%)

Frequency not reported: Peripheral edema[Ref]

Nervous system

Very common (10% or more): Dizziness (18.1%)

Common (1% to 10%): Headache[Ref]

Psychiatric

Very common (10% or more): Sleep disorder (34.9%)[Ref]

Hypersensitivity

Frequency not reported: Anaphylactic reaction

Postmarketing reports: Hypersensitivity reactions (including anaphylaxis, rash, angioedema, urticaria, lip and facial swelling, dyspnea, chest tightness, throat tightness)[Ref]

Cardiovascular

Frequency not reported: Asystole[Ref]

Dermatologic

Frequency not reported: Urticaria, dermatitis[Ref]

Respiratory

Frequency not reported: Rhinorrhea, acute pulmonary edema, acute pulmonary edema after aspirating the PEG-based preparation[Ref]

References

1. "Product Information. MoviPrep (polyethylene glycol 3350 with electrolytes)." Physicians Total Care, Tulsa, OK.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Hide