What is the difference between Plenvu and MoviPrep?

The main difference between MoviPrep and Plenvu is the total volume you must consume. Plenvu is also the only FDA-approved bowel cleanser to offer split dosing on the same day as the colonoscopy procedure.

Both MoviPrep and Plenvu are polyethylene glycol (PEG 3350)-based prescription osmotic laxatives used by adults 18 years of age and older, to clean the colon before a colonoscopy.

MoviPrep requires you to drink two liters of PEG and one additional liter of the clear liquid of your choice. Plenvu is a lower-volume PEG-based bowel preparation compared to MoviPrep. With Plenvu, you drink only one liter of PEG and one additional liter of the clear liquid of your choice.

Studies have shown that high-volume bowel preparations can often be a deterrent to patients fully completing their preparation regimen prior to their colonoscopy, and lower volume preparations may enhance adherence.