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What is the difference between Clenpiq and Prepopik?

Medically reviewed by Judith Stewart, BPharm. Last updated on May 26, 2021.

Official Answer

by Drugs.com

Prepopik (sodium picosulfate, magnesium oxide and citric acid) is supplied as a powder that must be reconstituted with cold water before use, while Clenpiq (sodium picosulfate, magnesium oxide and citric acid) is ready to drink and it does not need to be diluted prior to administration.

Prepopik and Clenpiq contain a combination of sodium picosulfate (a stimulant laxative), and magnesium oxide and citric acid which form magnesium citrate (an osmotic laxative). Both products are used in adults and pediatric patients ages 9 years and older for cleansing the colon in preparation for colonoscopy

Prepopik has been discontinued.

Clenpiq oral solution contains sodium picosulfate 10 mg, magnesium oxide 3.5 g, and anhydrous citric acid 12 g in 160 mL of solution.

  • Clenpiq is a ready to drink, cranberry-flavored oral solution that does not need to be diluted prior to administration.
  • Two doses (two 160 mL bottles) are required for a complete preparation for colonoscopy as a split-dose regimen. The first dose is administered the evening before the colonoscopy, and the second dose is administered the next day, during the morning prior to the colonoscopy.

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