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Polyethylene Glycol 3350 With Electrolytes Dosage

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Bowel Preparation

4 Liter preparations:
8 oz., orally, every 10 minutes, until the rectal effluent is clear or 4 liters are consumed
or
20 to 30 mL per minute, via a nasogastric tube

2 Liter preparations:
-Split-dose regimen:
8 oz., orally, every 15 minutes over 1 hour, then 0.5 L (approximately 16 oz.) of clear fluid the evening before colonoscopy; repeat this dosing the morning of the colonoscopy

-Evening only regimen:
8 oz., orally, every 15 minutes over 1 hour, the evening before the colonoscopy; about 1.5 hours later, 8 oz., orally, every 15 minutes over 1 hour
-An additional 1 liter (about 32 oz.) of clear liquid should be consumed the evening before the colonoscopy.
-Recommended start time is around 6 PM.

Comments:
-Product must be reconstituted prior to administration.
-Rapid drinking of each portion is preferred to drinking small amounts continuously.
-Avoid red and purple liquids when consuming clear fluids.

Use: Bowel cleansing prior to colonoscopy and barium enema X-ray examination

Usual Pediatric Dose for Bowel Preparation

6 months or older:
25 mL/kg/hour, orally or via a nasogastric tube, until the rectal effluent is clear

Comments:
-Not all products are approved for pediatric use; the manufacturer product information should be consulted.

Use: Bowel cleansing prior to colonoscopy and barium enema X-ray examination

Renal Dose Adjustments

Use with caution.
-Advise patients of the importance of adequate hydration.
-Consider performing baseline and post-procedure laboratory tests (electrolytes, creatinine, and BUN).

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 6 months.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-Product must be reconstituted prior to administration.
-Rapid drinking of each portion is preferred to drinking small amounts continuously.
-The patient should fast for 3 to 4 hours prior to starting this medication; no solid food should be given for at least 2 hours before the medication.
-Allow three hours for drinking and an additional hour for complete bowel evacuation.
-The solution is more palatable when chilled, but chilled solution is not recommended for infants.

Storage requirements:
-Store unreconstituted product at controlled room temperature.

Reconstitution/preparation techniques:
-If flavor packs are available, the preparation can be used with or without the flavor packs.
-If flavor packs are used, pour contents into bottle BEFORE reconstitution; shake well to incorporate flavoring into the powder.
-Add water to FILL line, replace cap tightly and shake well until all ingredients have dissolved.
-Do not add additional ingredients or flavorings to the solution.
-Dissolution is facilitated by using lukewarm water.

Patient advice:
-This medication produces a watery stool which cleanses the bowel prior to examination.
-Prepare the solution according to the package instructions.
-It is more palatable when chilled.
-For best results, don't consume solid food for 3 to 4 hours before drinking the solution; in no case should solid food be consumed within 2 hours of taking this medication.
-Continue drinking until the watery stool is clear and free of solid matter; this normally requires consuming 3 to 4 liters.
-Rapid drinking of each portion is better than drinking small amounts continuously.
-The first bowel movement occurs about 1 hour after starting this medication.
-If severe discomfort or distension occurs, stop drinking temporarily or drink each portion at longer intervals until the symptoms disappear.
-Oral medications taken within 1 hour of starting this medication may be flushed from the gastrointestinal tract and not absorbed.
-After the medication is taken, only clear liquids should be consumed. Avoid red and purple clear liquids.
-Discard any unused medication.

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