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Relistor and Constipation: What Users Say

Constipation: mentioned by 7 users (11.5%)

Based on user experiences from 61 Relistor reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

cramps 16.4%
constipation 11.5%
gas 11.5%
nausea 8.2%
sweating 8.2%
vomiting 6.6%
diarrhea 4.9%
upset stomach 4.9%
withdrawal 4.9%

Reviews for Relistor

Commonly mentioned side effects
  • Gio...
  • Taken for less than 1 month
  • August 17, 2018

For Opioid-Induced Constipation "I have the most difficult time going to the restroom after taking Norco. I would stay in the restroom for hours, pushing and pushing to the point where blood would come out. I was super constipated. I went to my doctor, and she gave me 150 mg 3 times in the morning, 30 minutes before a meal. Within 20 minutes, I got horrible stomach cramps. 1 hour after waiting, I was able to poop like a normal person and a lot came out! The stool was solid, and I didn’t have to strain. After I use the restroom, the cramps are gone! It’s weird, after taking the meds, I could feel everything being broken down and everything moving down to my rectum. Sorry if that is TMI, just wanted to share an honest opinion."

9 / 10
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  • Anonymous
  • July 8, 2015

For Constipation, Chronic "Nothing yet, not helping, on 3rd day I took 3 shots, but still, not worked... I am on my 8th shot today... going back to docs in the morning... I hurt, I feel tight, bloated... it feels it could rupture at any time... God, the constipation feels like death. I am so full, I don't feel I can eat or drink."

1 / 10
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41 Report
  • tub...
  • April 9, 2017

For Constipation, Drug Induced "I take Dilaudid because I am living with multiple sclerosis and have severe muscle spasms. Unfortunately, the Dilaudid has started making me constipated, so my doctor prescribed me Relistor injections, 12 mg (the higher dose - it depends on your weight). I took this medication for the first time this morning because I had not had a bowel movement in five days. I did the injection (beware, it burns when injecting!) and went on with my day. Within ten minutes (I'm not kidding), I had to use the restroom. Success! That's the good part. After my successful bowel movement came terrible abdominal pain. I mean, it wasn't like, 'I have to go to the ER' terrible, but it was significant enough that I am mentioning it. Overall, a good drug."

8 / 10
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36 Report

Frequently asked questions

  • Chr...
  • November 28, 2008

For Constipation, Drug Induced "I suffer from chronic pain and have been on and off opioid therapy for much of my adult life. Because I suffer from chronic pelvic pain, constipation is extremely painful for me. Unfortunately, natural and/or gentle laxatives were not strong enough for me, and strong laxatives were too hard on my system, so nothing was working for me until now. I have just started the treatments, so I am just taking a little less than the 4 ml dose, twice a week. So far, each time I have had my shot, I have had a 'normal' bowel movement within one hour. Overall, if you are struggling with constipation as a result of pain medications, this very well could be the solution for you. It has been for me."

8 / 10
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  • Pai...
  • Taken for 1 to 6 months
  • March 20, 2015

For Constipation, Drug Induced "I've had mixed results with this. Been on 180 mg of Oxy IR and 75 mcg Fentanyl for years. When my doc increased my Fentanyl to every 48 hours, all my plumbing stopped. I never had any problems, ever! I fought with the constipation, not going for 6 weeks+ sometimes. I don't know what hurts worse...? Anyway, the Relistor works here and there. I don't have insurance, and at $75 a 12 mg injection, I can't afford not to go!!! I just gave myself a 12 mg shot yesterday, and another today, 24 hrs apart. Nothing. I haven't gone in 3 weeks now. This is not good. The laxative route does nothing as well. I'm frustrated... Any suggestions?"

3 / 10
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17 Report

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  • Jal...
  • Taken for 1 to 6 months
  • April 2, 2015

For Constipation, Drug Induced "Constipation due to opiates has been extremely bad for me. Along with Relistor, I'm still taking laxatives and suppositories. I'm on my second month with one shot every other day, and only twice did I not have to use a suppository. Wondering if I have something else going on."

2 / 10
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  • Anonymous
  • April 11, 2010

For Constipation, Drug Induced "I've been going on and off opiates for around 8 years since my chronic pain began. I would go off the medicines to get relief from the horrible constipation they caused. A few years ago, I discovered that I was constipated even when I would go off the medicines, so I must have messed something up by using laxatives for so long. I tried the subcutaneous Relistor that I had been desperately waiting for for years, and unfortunately, it didn't help."

1 / 10
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22 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.