Skip to main content

Monistat 1 Combination Pack and Severe Pain: What Users Say

Severe pain: mentioned by 9 users (2.3%)

Based on user experiences from 394 Monistat 1 Combination Pack reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 67.8%
itching 47.2%
pain 18.0%
swelling 8.6%
discomfort 7.9%
irritation 6.1%
severe pain 2.3%
tingling 2.0%
bleeding 1.5%
chemical burn 1.3%

Reviews for Monistat 1 Combination Pack

Commonly mentioned side effects
  • wom...
  • Taken for less than 1 month
  • May 13, 2019

For Vaginal Yeast Infection "In the spirit of Game of Thrones’ final episodes and Arya being a badass, I like to think that were she confronted by the god of death, she would fling a filled applicator of this unholy concoction at death’s face and scream ‘not today!!’ and then the god of death’s face would burn, itch, melt, and burst into a thousand flames of agony. Seriously, it’s like one of Daenerys’s dragons got loose in my vagina and is clawing and fire-breathing on its way out. I know this is very silly, but it’s all I can do to keep from screaming and writhing in my bed like a possessed banshee because this stuff is mutilating my insides. In short, if the doc prescribes you antibiotics, just straight up ask him or her to circumvent the nonsense and prescribe Diflucan while they’re at it because antibiotics lead to yeast and yeast leads to Monistat and Monistat leads to wailing in agony. BRB gonna go put ice cubes up my bajingo now."

1 / 10
Was this helpful?YesNo
124 Report
  • Jay...
  • Taken for less than 1 month
  • November 16, 2019

For Vaginal Yeast Infection "Stay away!! I used Monistat over a decade ago. Some reviews say that the burning is because it’s not a yeast infection. Untrue! This Monistat is a different formula, and whatever they put in it causes extreme burning! My labia minor and major burned in ways I cannot describe. The inflammation is not minimal! Please don’t purchase this product. On day 1, there was some mild discomfort and itching. Day 2 was by far the worst as the product began to slowly seep out, and I was up all night in pain and agony. Day 3, the “chunks” of the egg start to come out, and I finally felt relief. It is now Day 4, and there is some itching, but barely noticeable. Don’t use this product. Please! The FDA needs to investigate this."

1 / 10
Was this helpful?YesNo
35 Report
  • Fir...
  • Taken for less than 1 month
  • December 16, 2019

For Vaginal Yeast Infection "So I should have read these reviews before I decided to put this egg of fire in my nether regions. I put it in at 3 am, fell asleep, and by 7 am I had a new meaning of fire crotch. Today is day two, now because Aunt Flo came around to make my life even worse. If you can stand the intense pain, then it works, but before I allow Satan's love child back in my whoha, I'll go to a doctor first. Maybe my princess triangle will be less mad at me when all this is over."

3 / 10
Was this helpful?YesNo
28 Report

See also:

Frequently asked questions

  • Hop...
  • December 6, 2021

For Vaginal Yeast Infection "Dear mother of holy hell. I literally feel like the literal goddamn sun is in between my labia. I am in extreme discomfort right now. How is this happening? Why isn't the box bright red with flames to give you a proper warning? Dear Lord. It’s finals week. I might as well dig my grave now."

1 / 10
Was this helpful?YesNo
5 Report
  • fir...
  • March 23, 2021

For Vaginal Yeast Infection "I developed a yeast infection from antibiotics and used Monistat 1 after a 7-day treatment didn't work. I was fine until I peed for the first time since using it, and I am in severe pain, terrible itching, and internal burning, and even bleeding. Do not use this product unless you’re prepared for an insane amount of pain and discomfort. I am currently sitting with an ice pack between my legs, trying to Google ways to flush this awful egg out."

1 / 10
Was this helpful?YesNo
2 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Bur...
  • Taken for less than 1 month
  • April 4, 2019

For Vaginal Yeast Infection "Took at 8 PM, and by 4 AM, I was woken out of my sleep by this excruciating pain. My lazy self should've just gone to the doctor since I have to now anyway. In the past, I've used the 3-day with no issue. I tried to get the egg out to no avail. Having to soak in a cold bath to alleviate any pain at this point."

1 / 10
Was this helpful?YesNo
2 Report
  • Kit...
  • Taken for less than 1 month
  • November 22, 2021

For Vaginal Yeast Infection "I will never buy a Monistat product again. After inserting the Monistat 1 capsule, I was in intense pain for about three hours, needing to take Advil and lie down. I then had a plastic-like discharge that looked like strips of plasticky tape. I actually felt better the next day. But a week later, I had to go to urgent care, as I had pain and more white discharge. I have never seen anything like the discharge I had that day. It was like big white clumps of cottony and plastic-like stuff. The doctor seemed surprised and confused, as all the swab tests came back negative, I have no infection! I believe the ovule somehow stuck inside of me or misfired. If I had the packaging and receipt, I would surely write the company a letter and let them know. I either had an older product, or something went wrong at the factory with this one. I will never use Monistat again, my gynecologist shook her head when I said I used it instead of coming to see her."

1 / 10
Was this helpful?YesNo
1 Report
  • Ano...
  • April 21, 2021

For Vaginal Yeast Infection "This was a mistake. The creation of this product, and me choosing to use it. I saw the warnings and didn’t heed them. I thought, “Oh, I have a high pain tolerance, it will be fine!” Oh my, was I wrong. I’m talking full ghost pepper fire in the nether regions, itchiness that made my spine seize up, and all other manner of unbearable pain. I was able to tough it out for a few hours, but after that, I just had to get it out. I sat on the toilet and got as much out as I could that way before running ice-cold bath water on the whole area. When it was numb enough for my tastes, I rubbed coconut oil all over. Trust me on this, coconut oil with a few optional drops of tea tree oil diluted in it are your best friends in this situation. It didn’t fully take away all of the burning or itching, but it definitely made it better. Don’t be like me and use the product even though people warned not to - genuinely, it doesn’t matter how high your pain tolerance is, this will make you suffer."

1 / 10
Was this helpful?YesNo
0 Report
  • kay...
  • Taken for less than 1 month
  • November 22, 2021

For Vaginal Yeast Infection "So I took Monistat 1 at around 12 a.m. Wednesday night, and it’s now Monday morning, and I’ve been dealing with burning and irritation for the past 4 days. It stopped the mild itching, but I have sharp pain in my vagina. I’m leaving to go on a trip for Thanksgiving, so I need this to stop. How long did it take for the burning to stop for y’all? Google says typically around 7 days it leaves your body, but literally I need this GONE before I escort myself to the ER."

1 / 10
Was this helpful?YesNo
0 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.