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Monistat 1 Combination Pack and Cramps: What Users Say

Cramps: mentioned by 6 users (1.5%)

Based on user experiences from 395 Monistat 1 Combination Pack reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 67.6%
itching 47.1%
pain 18.0%
swelling 8.6%
discomfort 7.8%
irritation 6.1%
severe pain 2.3%
tingling 2.0%
bleeding 1.5%
cramps 1.5%

Reviews for Monistat 1 Combination Pack

Commonly mentioned side effects
  • Doi...
  • January 1, 2022

For Vaginal Yeast Infection "I took a shower so that I was clean. Inserted the egg, and directly after, I used the cream. Walked around my house doing chores and such. Had slight cramping and a 'cold' tingle, but nothing crazy. I think the cream numbs the pain. I used it every 4 hours, and I didn't suffer. Highly recommend using a panty liner as the cream discharges as the egg is dissolved."

10 / 10
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  • Fir...
  • Taken for less than 1 month
  • October 17, 2018

For Vaginal Yeast Infection "Same like most of you, I had a really junk experience! I put it in around midnight, woke up around 2 am to pee, and OMG! I seriously wanted to rip my kitty off! She was extremely itchy and burning! I jumped in the shower and just rinsed it! It kinda helped. After I got out, I ended up using a cream that I already had from my last YI a couple of years ago called nystatin and triamcinolone acetonide cream. That helped some. (My last YI I went to the doctors and got prescribed the pill.) When I woke up in the morning, I had really bad cramps that haven’t gone away. Discharge is not a lot but there. Also, I have some rash in my vagina! Technically, it hasn’t been a full 24 hours yet, midnight is in a couple of hours, so I hope that I feel better soon. I do not recommend this product at all!!! I wish I had read reviews first :( I should not have been lazy to go see my doctor!"

1 / 10
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2 Report
  • Hot...
  • Taken for less than 1 month
  • April 2, 2018

For Vaginal Yeast Infection "I'd been experiencing a painful itch for a few days down there, and I immediately suspected a YI. So on Friday, I paid $24.00 for the combo pack for the new Monistat with the Ovule. I'd used Monistat 7 days before, but I wanted to cut corners. I live a busy lifestyle. SHAME ON ME. I went home, put the kids to bed, showered, and inserted the ovule. The wipes provided some relief, and I should have stopped there. I was chilling on the couch, and my cha-cha was on FIRE. I was queasy and nearly threw up. I thought I was dying, and the only thing stopping me from going to the hospital was the crushing FEAR that someone would have to see my poor, red, beaten-up swollen cha-cha that was now oozing medication. It's now Sunday, and I'm still mildly cramping, cranky, and the medicine is still seeping out. With every gross seep, a wave of pain hits. If I could rate this medicine a fat '0,' I would. Don't put this stuff anywhere near your lady parts. You'll wish you'd have stayed infected."

1 / 10
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1 Report

Frequently asked questions

  • Thi...
  • Taken for less than 1 month
  • June 7, 2018

For Vaginal Yeast Infection "It’s been a very long time since I had a yeast infection. I bought Monistat 1 day treatment because it was a brand I recognized. It was bearable before, but after 4 hours it has gotten way worse. It itches more than it did before. And now I am having light cramps. I’m about to go shower to try and get some relief. An ice pack between the thighs is not helping."

1 / 10
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  • Dan...
  • Taken for less than 1 month
  • August 11, 2021

For Vaginal Yeast Infection "Confused as to why they don't put a bigger warning label on this. After reading these reviews, it's obvious that more than half of women experience this 'I stuck my vagina over a flame' burning. I didn't think of even looking at reviews before purchasing, just wanted to get rid of the annoying YI. Slipped in this stupid egg, and like everyone else, an hour later, I felt like Dante's Inferno opened up in my body. Tried peeing and realized that makes it worse. Three hours after insertion and I can already tell you this is my life's biggest regret. I popped three Advil and the pain is subsiding a smidge. Along with the burning, I'm also having cramps and noticed light pink discharge. Hopefully, this ball of lava isn't destroying my organs... good luck to everyone and take Tylenol 1500s with this one."

1 / 10
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  • Ano...
  • July 22, 2025

For Vaginal Yeast Infection "Soon after insertion, it made me have slight cramping and nausea. Felt fine prior to inserting, only started feeling lower stomach cramps and nausea about 20-30 mins later. No burning or itching."

5 / 10
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