Zetia Alternatives Compared
| Zetia | Atorvastatin | Simvastatin |
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| Zetia ezetimibe | Atorvastatin | Simvastatin |
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Zetia may be used to lower cholesterol alone or in combination with a statin or fibrate. It has few reported side effects and few drug interactions. It is effective at lowering intestinal absorption... View more |
Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Prescribed for High Cholesterol, High Cholesterol - Familial Heterozygous... View more |
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain particularly at higher dosages. Prescribed for High Cholesterol, Cardiovascular Risk Reduction, High Cholesterol -... View more |
Choose a suggestion below High Cholesterol
High Cholesterol, Familial Heterozygous
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| More about Zetia (ezetimibe) | More about Atorvastatin | More about Simvastatin | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Zetia has an average rating of 4.3 out of 10 from a total of 63 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 57% reported a negative effect. |
Atorvastatin has an average rating of 4.4 out of 10 from a total of 255 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 55% reported a negative effect. |
Simvastatin has an average rating of 4.8 out of 10 from a total of 123 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 49% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full Zetia side effects document. |
Commonly reported side effects include: hemorrhagic stroke, arthralgia, diarrhea, nasopharyngitis. See the full atorvastatin side effects document. |
See the full simvastatin side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zetia prices and generic prices |
View all atorvastatin prices |
View all simvastatin prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Lipitor | FloLipid, Zocor | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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22 hours |
14 hours |
N/A |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 37 drugs are known to interact with Zetia:
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A total of 335 drugs are known to interact with atorvastatin:
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A total of 281 drugs are known to interact with simvastatin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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October 25, 2002 |
December 17, 1996 |
December 23, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.