Comparing Repatha vs Zetia
| Repatha (evolocumab) | Zetia (ezetimibe) |
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| Repatha (evolocumab) | Zetia (ezetimibe) |
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Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Zetia may be used to lower cholesterol alone or in combination with a statin or fibrate. It has few reported side effects and few drug interactions. It is effective at lowering intestinal absorption... View more |
Related suggestions High Cholesterol
High Cholesterol, Familial Heterozygous
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| More about Repatha (evolocumab) | More about Zetia (ezetimibe) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Repatha has an average rating of 5.4 out of 10 from a total of 715 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 44% reported a negative effect. |
Zetia has an average rating of 4.3 out of 10 from a total of 76 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 57% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Repatha side effects |
View all Zetia side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Repatha prices |
View all Zetia prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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408 hours |
22 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 3 drugs are known to interact with Repatha:
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A total of 68 drugs are known to interact with Zetia:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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August 27, 2015 |
October 25, 2002 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Zetia
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Pravastatin
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Simvastatin
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.