Trulicity Alternatives Compared
Trulicity | Mounjaro | Metformin |
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Trulicity (dulaglutide) | Mounjaro (tirzepatide) | Metformin |
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Prescription only
Trulicity mimics the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It lowers blood glucose levels in people with... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Diabetes - Type 2. Mounjaro may also be used for purposes not listed in this medication guide. |
Prescription only
Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more |
Related suggestions Diabetes, Type 2
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More about Trulicity (dulaglutide) | More about Mounjaro (tirzepatide) | More about Metformin | ||||||||||||||||||||||||
Generic Status | ||||||||||||||||||||||||||
No lower-cost generic available |
No lower-cost generic available |
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Ratings & Reviews | ||||||||||||||||||||||||||
Trulicity has an average rating of 5.2 out of 10 from a total of 962 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 41% reported a negative effect. |
Mounjaro has an average rating of 8.5 out of 10 from a total of 817 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 8% reported a negative effect. |
Metformin has an average rating of 6.9 out of 10 from a total of 650 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Trulicity side effects in more detail. |
See also: Mounjaro side effects in more detail. |
See also: metformin side effects in more detail. |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Trulicity prices |
View all Mounjaro prices |
View all metformin prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
Other tirzepatide brands include: Zepbound | Glumetza | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
120 hours |
120 hours |
4.5 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 253 drugs are known to interact with Trulicity:
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A total of 397 drugs are known to interact with Mounjaro:
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A total of 365 drugs are known to interact with metformin:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
September 18, 2014 |
N/A |
March 03, 1995 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.