Trulicity Alternatives Compared
| Trulicity (dulaglutide) | Ozempic (semaglutide) | Rybelsus (semaglutide) |
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| Trulicity (dulaglutide) | Ozempic (semaglutide) | Rybelsus (semaglutide) |
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Prescription only
Trulicity mimics the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It lowers blood glucose levels in people with... View more |
Prescription only
Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Related suggestions Type 2 Diabetes
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| More about Trulicity (dulaglutide) | More about Ozempic (semaglutide) | More about Rybelsus (semaglutide) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Trulicity has an average rating of 5.3 out of 10 from a total of 970 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 40% reported a negative effect. |
Ozempic has an average rating of 6.6 out of 10 from a total of 1526 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Rybelsus has an average rating of 6.4 out of 10 from a total of 290 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Trulicity side effects |
View all Ozempic side effects |
View all Rybelsus side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Trulicity prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Rybelsus prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
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N/A |
Other semaglutide brands include: Rybelsus, Wegovy | Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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120 hours |
168 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 271 drugs are known to interact with Trulicity:
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A total of 273 drugs are known to interact with Ozempic:
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A total of 273 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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September 18, 2014 |
N/A |
September 20, 2019 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Wegovy
Wegovy (semaglutide) an FDA-approved weekly injection for weight loss and to reduce heart risks ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Mounjaro
Mounjaro (tirzepatide) is FDA-approved to manage type 2 diabetes in adults. It lowers blood sugar ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Repatha
Repatha is used to lower high cholesterol alongside dietary changes and to reduce the risk of major ...
Jardiance
Jardiance (empagliflozin) is used to treat type 2 diabetes, chronic kidney disease and reduce the ...
Xarelto
Xarelto (rivaroxaban) is a factor Xa inhibitor used to reduce the risk of blood clots and stroke in ...
Lantus
Lantus is a long acting form of insulin used to treat type 1 or type 2 diabetes. Learn about side ...
Tresiba
Tresiba (insulin degludec) is used to treat diabetes mellitus. Includes Tresiba side effects ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.