Comparing Rybelsus vs Metformin
Rybelsus (semaglutide) | Metformin |
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Rybelsus (semaglutide) | Metformin |
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Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Prescription only
Metformin improves how the body responds to insulin and it is used to treat type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side effects. Metformin is... View more |
Related suggestions Type 2 Diabetes
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More about Rybelsus (semaglutide) | More about Metformin | ||||||||
Ratings & Reviews | |||||||||
Rybelsus has an average rating of 6.5 out of 10 from a total of 315 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 22% reported a negative effect. |
Metformin has an average rating of 6.8 out of 10 from a total of 660 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 19% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Rybelsus side effects |
View all Metformin side effects |
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Drug Class | |||||||||
Generic Availability | |||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Metformin prices |
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Dosage Forms | |||||||||
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Brand Names | |||||||||
Other semaglutide brands include: Ozempic, Wegovy | Glumetza | ||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
168 hours |
4.5 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 275 drugs are known to interact with Rybelsus:
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A total of 381 drugs are known to interact with Metformin:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
September 20, 2019 |
March 03, 1995 |
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WADA Class View classifications | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient Resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.