Comparing Mounjaro vs Rybelsus
| Mounjaro (tirzepatide) | Rybelsus (semaglutide) |
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| Mounjaro (tirzepatide) | Rybelsus (semaglutide) |
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Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Type 2 Diabetes. Mounjaro may also be used for purposes not listed in this medication guide. |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Related suggestions Type 2 Diabetes
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| More about Mounjaro (tirzepatide) | More about Rybelsus (semaglutide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Mounjaro has an average rating of 8.5 out of 10 from a total of 1278 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect. |
Rybelsus has an average rating of 6.4 out of 10 from a total of 282 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Mounjaro side effects |
View all Rybelsus side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Mounjaro prices |
View all Rybelsus prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other tirzepatide brands include: Zepbound | Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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120 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 414 drugs are known to interact with Mounjaro:
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A total of 273 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
September 20, 2019 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.