Comparing Ozempic vs Rybelsus
| Ozempic (semaglutide) | Rybelsus (semaglutide) |
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| Ozempic (semaglutide) | Rybelsus (semaglutide) |
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Prescription only
Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Related suggestions Type 2 Diabetes
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| More about Ozempic (semaglutide) | More about Rybelsus (semaglutide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Ozempic has an average rating of 6.7 out of 10 from a total of 1543 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Rybelsus has an average rating of 6.4 out of 10 from a total of 297 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Ozempic side effects |
View all Rybelsus side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Ozempic prices |
View all Rybelsus prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other semaglutide brands include: Rybelsus, Wegovy | Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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168 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 273 drugs are known to interact with Ozempic:
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A total of 273 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
September 20, 2019 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.