Comparing Promethazine vs Trazodone
Promethazine | Trazodone |
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Promethazine | Trazodone |
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Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Related suggestions |
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More about Promethazine | More about Trazodone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Promethazine has an average rating of 7.2 out of 10 from a total of 398 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
Trazodone has an average rating of 6.3 out of 10 from a total of 1447 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Promethazine side effects |
View all Trazodone side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Promethazine prices |
View all Trazodone prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | Raldesy | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
16 hours |
7.5 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 692 drugs are known to interact with Promethazine:
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A total of 677 drugs are known to interact with Trazodone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
March 29, 1951 |
December 24, 1981 |
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WADA Class View classifications | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.