Paxil Alternatives Compared
| Paxil (paroxetine) | Rexulti (brexpiprazole) | Bupropion |
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| Paxil (paroxetine) | Rexulti (brexpiprazole) | Bupropion |
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Prescription only
Paxil may be used for the treatment of depression, anxiety, or post-traumatic stress disorder. It should be tapered off slowly on discontinuation. Prescribed for Anxiety and Stress, Dysautonomia... View more |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Related suggestions Depression
Major Depressive Disorder
Popular comparisons
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| More about Paxil (paroxetine) | More about Rexulti (brexpiprazole) | More about Bupropion | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Paxil has an average rating of 7.1 out of 10 from a total of 960 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 20% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 490 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 26% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2900 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Paxil side effects |
View all Rexulti side effects |
View all Bupropion side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Paxil prices |
View all Rexulti prices |
View all Bupropion prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other paroxetine brands include: Brisdelle, Paxil CR |
N/A |
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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21 hours |
91 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 509 drugs are known to interact with Paxil:
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A total of 600 drugs are known to interact with Rexulti:
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A total of 559 drugs are known to interact with Bupropion:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 29, 1992 |
July 10, 2015 |
December 30, 1985 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.