Nicorette Alternatives Compared
Nicorette | Bupropion | Varenicline |
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Nicorette (nicotine) | Bupropion | Varenicline |
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Prescription and OTC
Prescribed for Smoking Cessation. Nicorette may also be used for purposes not listed in this medication guide. |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Prescribed for Smoking Cessation, Dry Eye Disease. varenicline may also be used for purposes not listed in this medication guide. |
Related suggestions Smoking Cessation
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More about Nicorette (nicotine) | More about Bupropion | More about Varenicline | ||||||||||||||||||||||||
Generic Status | ||||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Nicorette has an average rating of 6.2 out of 10 from a total of 39 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 38% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2856 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
Varenicline has an average rating of 8.6 out of 10 from a total of 1697 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 9% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Nicorette side effects in more detail. |
See also: bupropion side effects in more detail. |
See also: varenicline side effects in more detail. |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nicorette prices and generic prices |
View all bupropion prices |
View all varenicline prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other nicotine brands include: Commit, Habitrol, Leader Nicotine Polacrilex, Nicoderm CQ, Nicorette DS, Nicotrol Inhaler, Nicotrol NS | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Champix, Tyrvaya | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
4 hours |
30 hours |
24 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 31 drugs are known to interact with Nicorette:
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A total of 497 drugs are known to interact with bupropion:
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A total of 8 drugs are known to interact with varenicline:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
January 13, 1984 |
December 30, 1985 |
May 10, 2006 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.