Comparing Naltrexone vs Sertraline

For Alcohol Dependence I started taking a daily dose 3 days ago. I poured myself a drink today as an 'experiment', and noticed right away the smell of the alcohol seemed different and was a real turn-off. I nursed the drink for almost an hour, which is almost unheard of for me (I'm a chugger). I finished the drink more out of obligation of the experiment than anything, and I never got the usual 'buzz' I'd get. Now I have a slight headache and I'm a bit tired. Honestly, if any future drinking feels like this then I can definitely see how this will curb my drinking as there is no reward anymore. And I've been trying to get control of this for 10+ years, therapy, counselling, rehab, AA, etc.

For Alcohol Dependence It's day 4 for me on naltrexone. First day I took 25mg and it made me a little sedated. Went to dinner, couldn't finish my wine, had a glass later knowing cold turkey is a bad idea. I was 1 to 1.5 bottle of wine drinker daily. Next night took a 12.5mg, had maybe 6 oz wine, next night 2 corona lights, and next night one beer. No cravings at all, no shaking. I had some irritability but I think that's to be expected. This drug has made is easy to wean off alcohol. Alcoholism killed my father and ruined my marriage. Both of us drank. No bueno. I am very vocal with family about my desire to quit. I tried a few times before and naltrexone is a godsend. Good luck all!

For Depression 19 yr old male going on 20. Had been suffering from extreme anxiety, depression, paranoia, intrusive thoughts for the best part of a year. Day to day life was a living hell and I rapidly began to lose any motivation and hope I had left. Started on 50mg, probably made things worse for first 4 weeks, upped to 100mg, wouldn't class it as life changing, anxiety and thoughts are still there, but a lot less intense. Much chirpier and can finally engage in day to day life with a lot more ease and comfort without feeling completely messed up and hopeless. Would recommend, just hang on in there. Things do get better.

For Depression Long story short. I have suffered depression for 20+ years and anxiety for the last year which led me to resign from a stressful management position, my co worker recommended zoloft, my GP started me on 50mg which I took for 2 weeks, my dose was increased to 100mg, it has now been about 6 weeks, I had very few side affects for a few days, slight insomnia, loss of appetite (have lost quite a few kgs) and a little jaw clenching, I feel a lot calmer, I have a little more interest in activities, showering, cooking and cleaning more which are all great results, family members have noticed subtle changes, laughing/smiling and doing more, In saying that I feel as though my dose needs to be increased but will give it 2 weeks, Give it time:)