Comparing Naltrexone vs Sertraline

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Naltrexone

Sertraline

Naltrexone is used as an adjunct to social and psychotherapy in the treatment of opioid and alcohol addiction. People taking naltrexone need to have completely stopped taking all types of opioids... View more

Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Prescribed for Panic Disorder, Obsessive Compulsive Disorder, Major Depressive Disorder... View more

Prescription only

Ratings & Reviews

View all 505 reviews

View all 3674 reviews

Drug Class

Selective serotonin reuptake inhibitors

Side Effects

Commonly reported side effects include: streptococcal pharyngitis, syncope, anxiety, arthralgia, arthritis, dizziness, drowsiness, fatigue, frequent headaches, headache, joint stiffness, nasopharyngitis, nausea, nervousness, obsessive compulsive disorder, panic attack, pharyngitis, posttraumatic stress disorder, sedated state, sinus headache, vomiting, induration at injection site, malaise, pain at injection site, and tenderness at injection site.

See the full naltrexone side effects document.

Commonly reported side effects include: diarrhea, dizziness, drowsiness, dyspepsia, fatigue, insomnia, loose stools, nausea, tremor, headache, paresthesia, anorexia, decreased libido, delayed ejaculation, diaphoresis, ejaculation failure, and xerostomia.

See the full sertraline side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	30 each
Dosage	50 mg
Per Unit^*	$1.81
Cost^*	$54.34

View all naltrexone prices

Quantity	100 each
Dosage	100 mg
Per Unit^*	$0.55 - $0.56
Cost^*	$54.65 - $56.06

View all sertraline prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral tablet

Oral concentrate
Oral tablet

Brand Names

Vivitrol Zercapli, Zoloft

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

10 hours

66 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Drug Interactions

A total of 313 drugs are known to interact with naltrexone:

33 major drug interactions (157 brand and generic names)
280 moderate drug interactions (1204 brand and generic names)

A total of 624 drugs are known to interact with sertraline:

143 major drug interactions (564 brand and generic names)
474 moderate drug interactions (1948 brand and generic names)
7 minor drug interactions (35 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Naltrexone may cause liver problems, and using it with other medications that can also affect the... View more

You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol can... View more

Disease Interactions

First Approval Date

April 13, 2006

December 30, 1991

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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