Comparing Methadone vs Vicodin
| Methadone | Vicodin (acetaminophen / hydrocodone) |
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| Methadone | Vicodin (acetaminophen / hydrocodone) |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Vicodin is a combination narcotic analgesic that may be used short-term for the relief of moderate-to-moderately severe pain that is unrelieved by nonopioid analgesics, and also for the relief of a... View more |
Related suggestions |
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| More about Methadone | More about Vicodin (acetaminophen / hydrocodone) | ||||||||
| Ratings & Reviews | |||||||||
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Methadone has an average rating of 8.7 out of 10 from a total of 606 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 6% reported a negative effect. |
Vicodin has an average rating of 7.7 out of 10 from a total of 146 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Methadone side effects |
View all Vicodin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Methadone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Methadone Diskets, Methadose, Methadose Sugar-Free | Other acetaminophen / hydrocodone brands include: Xodol, Zyfrel | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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30 hours |
3.8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 836 drugs are known to interact with Methadone:
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A total of 682 drugs are known to interact with Vicodin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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August 13, 1947 |
January 07, 1983 |
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| WADA Class View classifications | |||||||||
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N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.