Comparing Methadone vs Vicodin
| Methadone | Vicodin (acetaminophen / hydrocodone) |
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| Methadone | Vicodin (acetaminophen / hydrocodone) |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Vicodin is a combination narcotic analgesic that may be used short-term for the relief of moderate-to-moderately severe pain that is unrelieved by nonopioid analgesics, and also for the relief of a... View more |
Related suggestions |
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| More about Methadone | More about Vicodin (acetaminophen / hydrocodone) | ||||||||
| Ratings & Reviews | |||||||||
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Methadone has an average rating of 8.7 out of 10 from a total of 606 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 6% reported a negative effect. |
Vicodin has an average rating of 7.7 out of 10 from a total of 146 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Methadone side effects |
View all Vicodin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Methadone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Methadone Diskets, Methadose, Methadose Sugar-Free | Other acetaminophen / hydrocodone brands include: Xodol, Zyfrel | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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30 hours |
3.8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 837 drugs are known to interact with Methadone:
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A total of 681 drugs are known to interact with Vicodin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
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| First Approval Date | |||||||||
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August 13, 1947 |
January 07, 1983 |
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| WADA Class View classifications | |||||||||
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N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.