Loratadine Alternatives Compared
| Loratadine | Zyrtec | Cetirizine |
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| Loratadine | Zyrtec cetirizine | Cetirizine |
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Loratadine is an antihistamine that effectively treats allergic-type reactions such as hay fever and is unlikely to cause drowsiness. Prescribed for Urticaria, Allergic Rhinitis, Allergic Reactions... View more |
Zyrtec is an antihistamine that effectively treats allergic-type reactions such as hay fever or skin reactions caused by insect bites. Although drowsiness with Zyrtec is uncommon, Zyrtec is more... View more |
Cetirizine is an antihistamine that effectively treats allergic-type reactions such as hay fever or skin reactions caused by insect bites. Although drowsiness with cetirizine is uncommon, cetirizine... View more |
Choose a suggestion below Allergic Rhinitis
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| More about Loratadine | More about Zyrtec (cetirizine) | More about Cetirizine | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription and OTC |
Prescription and OTC |
Prescription and OTC |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Loratadine has an average rating of 5.0 out of 10 from a total of 112 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 50% reported a negative effect. |
Zyrtec has an average rating of 5.9 out of 10 from a total of 180 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 35% reported a negative effect. |
Cetirizine has an average rating of 5.8 out of 10 from a total of 259 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 36% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See the full loratadine side effects document. |
See the full Zyrtec side effects document. |
See the full cetirizine side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all loratadine prices |
View all Zyrtec prices and generic prices |
View all cetirizine prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Alavert, Allergy Relief 24 Hour, Allergy Relief Tablets, Bactimicina Allergy, Children's Allergy Relief 24 Hour, Children's Claritin Allergy, Claritin, Claritin 24 Hour Allergy, Claritin Reditabs, Clear-Atadine Children's, Help I Have Allergies, Loratadine Reditab, ohm Allergy Relief, Tavist ND, Wal-itin View more | Other cetirizine brands include: All Day Allergy, All Day Allergy Children's, Aller-Tec, Aller-Tec Children's, Alleroff, Children's Allergy Relief, Equate Allergy Relief, PediaCare Children's 24-Hour Allergy, Quzyttir, Zyrtec Hives View more | All Day Allergy, All Day Allergy Children's, Aller-Tec, Aller-Tec Children's, Alleroff, Children's Allergy Relief, Equate Allergy Relief, PediaCare Children's 24-Hour Allergy, Quzyttir, Zyrtec, Zyrtec Hives View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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18 hours |
10.6 hours |
10.6 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 85 drugs are known to interact with loratadine:
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A total of 248 drugs are known to interact with Zyrtec:
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A total of 248 drugs are known to interact with cetirizine:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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April 12, 1993 |
September 27, 1996 |
December 08, 1995 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.