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Loratadine Drug Interactions

A total of 88 drugs are known to interact with loratadine.

  • 73 moderate drug interactions
  • 15 minor drug interactions

Show all medications in the database that may interact with loratadine.

Check for interactions with loratadine

Type in a drug name and select a drug from the list.

Common medications checked in combination with loratadine

  • Advair Diskus (fluticasone / salmeterol)
  • Advil (ibuprofen)
  • Aspirin Low Strength (aspirin)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • Benadryl (diphenhydramine)
  • Cymbalta (duloxetine)
  • diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Unisom SleepGels, Dicopanol, Sleep, Diphenhist, Sominex, Diphen, Diphenadryl, Benadryl Children's Allergy, Allermax, Diphenydramine Quick Melt, Nytol, Diphedryl, Hydramine, Diphendryl, Pharbedryl, Buckley's Bedtime, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen Cough, DPH, Allergia-C, Q-Dryl, Sleep Tabs, Quenalin, Sleep-ettes D, Q-Dryl A/F, Dytan, Vanamine PD, Sleepwell 2-nite, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, 40 Winks, Diphen AF, Aler-Dryl, Benahist-10, Benahist-50, Benoject-50, Calm-Aid, Genahist, Alka-Seltzer Plus Allergy, Aller-G-Time, Sleep Tab II, Sleep-Eze-3, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Valu-Dryl, Diphenyl, Altaryl, Triaminic Thin Strips Cough & Runny Nose, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Sleep-ettes, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Uni-Tann, Diphenmax, Nightime Sleepaid, Ben-Tann, Histaprin, Z-Sleep, Tranquil Nighttime Sleep Aid, Unisom SleepMelts, PediaCare Children's Allergy, Truxadryl, Simply Sleep, Complete Allergy Relief, Dytuss, Dormin, Miles Nervine, Scot-Tussin Allergy)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • Flonase (fluticasone nasal)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Lexapro (escitalopram)
  • Lyrica (pregabalin)
  • MiraLax (polyethylene glycol 3350)
  • Mucinex (guaifenesin)
  • Nexium (esomeprazole)
  • Norco (acetaminophen / hydrocodone)
  • phentermine (Adipex-P, Lomaira, Fastin, Ionamin, Suprenza, Obenix, Atti-Plex P, Pro-Fast HS, Phentercot, Oby-Cap, Phentride, Obephen, Panshape M, Pro-Fast SR, T-Diet, Zantryl, Oby-Trim, Teramine, Pro-Fast SA, Teramine ER)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • ProAir HFA (albuterol)
  • pseudoephedrine (Sudafed Congestion, SudoGest, Sudafed 12-Hour, Entex, Sudafed Children's Nasal Decongestant, Suphedrine, Efidac, Cenafed, Chlor-Trimeton Nasal Decongestant, Contac Cold, Drixoral Decongestant Non-Drowsy, Nexafed Nasal Decongestant, nasofed, Silfedrine, Suphedrin, ElixSure Congestion, Children's Dimetapp Decongestant Infant, Allermed, Novafed, Genaphed, Ridafed, Seudotabs, Sudrine, Superfed, Afrinol, Zephrex-D, Decofed Liquid, Decofed, Kid Kare Drops, Myfedrine, Sudodrin, Elixsure Decongestant, Unifed, Sudafed 24-Hour, SudoGest 12 Hour, 12 Hour Decongestant, 12 Hour Nasal Decongestant)
  • Singulair (montelukast)
  • Symbicort (budesonide / formoterol)
  • Synthroid (levothyroxine)
  • Tylenol (acetaminophen)
  • Ventolin HFA (albuterol)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zoloft (sertraline)
  • Zyrtec (cetirizine)

Loratadine alcohol/food interactions

There is 1 alcohol/food interaction with loratadine

Loratadine disease interactions

There is 1 disease interaction with loratadine:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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