Lithium Alternatives Compared
| Lithium | Lybalvi (olanzapine / samidorphan) | Fanapt (iloperidone) |
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| Lithium | Lybalvi (olanzapine / samidorphan) | Fanapt (iloperidone) |
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Prescription only
Lithium may be used to treat manic episodes associated with bipolar I disorder; however, there is a fine line between too much and too little, and ongoing monitoring is needed to prevent lithium... View more |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia. Lybalvi may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Bipolar Disorder, Schizophrenia, Psychosis. Fanapt may also be used for purposes not listed in this medication guide. |
Related suggestions Bipolar Disorder
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| More about Lithium | More about Lybalvi (olanzapine / samidorphan) | More about Fanapt (iloperidone) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Lithium has an average rating of 7.3 out of 10 from a total of 491 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
Lybalvi has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 6% reported a negative effect. |
Fanapt has an average rating of 6.4 out of 10 from a total of 30 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Lithium side effects |
View all Lybalvi side effects |
View all Fanapt side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Lithium prices |
View all Lybalvi prices |
View all Fanapt prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Lithium Carbonate ER, Lithobid |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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29 hours |
54 hours (empirically) |
37 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 723 drugs are known to interact with Lithium:
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A total of 702 drugs are known to interact with Lybalvi:
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A total of 678 drugs are known to interact with Fanapt:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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April 06, 1970 |
May 28, 2021 |
May 06, 2009 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.