Lithium Alternatives Compared
| Lithium | Vraylar (cariprazine) | Caplyta (lumateperone) |
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| Lithium | Vraylar (cariprazine) | Caplyta (lumateperone) |
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Prescription only
Lithium may be used to treat manic episodes associated with bipolar I disorder; however, there is a fine line between too much and too little, and ongoing monitoring is needed to prevent lithium... View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Prescription only
Caplyta is an atypical antipsychotic that is used to treat adults with schizophrenia or depression associated with bipolar disorder. Sleepiness is the most common side effect and it should not be... View more |
Related suggestions Bipolar Disorder
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| More about Lithium | More about Vraylar (cariprazine) | More about Caplyta (lumateperone) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Lithium has an average rating of 7.3 out of 10 from a total of 492 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 524 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 32% reported a negative effect. |
Caplyta has an average rating of 6.6 out of 10 from a total of 185 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Lithium side effects |
View all Vraylar side effects |
View all Caplyta side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Lithium prices |
View all Vraylar prices |
View all Caplyta prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Lithium Carbonate ER, Lithobid |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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29 hours |
504 hours |
18 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 723 drugs are known to interact with Lithium:
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A total of 577 drugs are known to interact with Vraylar:
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A total of 605 drugs are known to interact with Caplyta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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April 06, 1970 |
September 17, 2015 |
December 20, 2019 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Abilify
Abilify is an antipsychotic medicine used to treat the symptoms of schizophrenia and bipolar ...
Caplyta
Caplyta is used to treat schizophrenia or depression associated with bipolar disorder. It is taken ...
Seroquel
Seroquel is used to treat the symptoms of schizophrenia, bipolar disorder and major depressive ...
Prozac
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Lamictal
Lamictal is an anti-epileptic medication used treat seizures in adults and children over 2 years ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Zyprexa
Zyprexa (olanzapine) is an atypical antipsychotic that may be used to treat adults and adolescents ...
Latuda
Latuda information from Drugs.com, includes Latuda side effects, interactions and indications.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.