Comparing Divalproex Sodium vs Lithium
| Divalproex sodium | Lithium |
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| Divalproex sodium | Lithium |
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Prescription only
Divalproex may be used for the treatment of absence or partial seizures, as a preventive treatment for migraines, and to treat mania associated with bipolar disorder. Divalproex may adversely and... View more |
Prescription only
Lithium may be used to treat manic episodes associated with bipolar I disorder; however, there is a fine line between too much and too little, and ongoing monitoring is needed to prevent lithium... View more |
Related suggestions Bipolar Disorder
Borderline Personality Disorder
Cyclothymic Disorder
Popular comparisons
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| More about Divalproex sodium | More about Lithium | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Divalproex sodium has an average rating of 6.6 out of 10 from a total of 509 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Lithium has an average rating of 7.3 out of 10 from a total of 491 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Divalproex sodium side effects |
View all Lithium side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Divalproex sodium prices |
View all Lithium prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Depakote, Depakote ER, Depakote Sprinkles | Lithium Carbonate ER, Lithobid | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
29 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 424 drugs are known to interact with Divalproex sodium:
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A total of 723 drugs are known to interact with Lithium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 10, 1983 |
April 06, 1970 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.