Comparing Lamotrigine vs Topiramate
| Lamotrigine | Topiramate |
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| Lamotrigine | Topiramate |
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Prescription only
Lamotrigine is used to decrease the frequency and severity of seizures in some types of epilepsy and also to stabilize mood in bipolar I disorder. It is an oral tablet that is taken once or twice a... View more |
Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
Seizures
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| More about Lamotrigine | More about Topiramate | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lamotrigine has an average rating of 7.8 out of 10 from a total of 1841 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 15% reported a negative effect. |
Topiramate has an average rating of 6.3 out of 10 from a total of 1332 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 28% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Lamotrigine side effects |
View all Topiramate side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lamotrigine prices |
View all Topiramate prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR, Subvenite | Eprontia, Qudexy XR, Topamax, Trokendi XR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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25.7 hours |
56 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 286 drugs are known to interact with Lamotrigine:
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A total of 291 drugs are known to interact with Topiramate:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 27, 1994 |
December 24, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.