Comparing Invokana vs Rybelsus
| Invokana (canagliflozin) | Rybelsus (semaglutide) |
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| Invokana (canagliflozin) | Rybelsus (semaglutide) |
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Prescription only
Invokana is effective at lowering blood glucose levels in people with type 2 diabetes. It also reduces the risk of future cardiovascular events (such as a heart attack or stroke) and kidney disease... View more |
Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Related suggestions Type 2 Diabetes
Popular comparisons
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| More about Invokana (canagliflozin) | More about Rybelsus (semaglutide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Invokana has an average rating of 5.8 out of 10 from a total of 257 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 35% reported a negative effect. |
Rybelsus has an average rating of 6.5 out of 10 from a total of 305 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Invokana side effects |
View all Rybelsus side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Invokana prices |
View all Rybelsus prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other semaglutide brands include: Ozempic, Wegovy | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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13.1 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 391 drugs are known to interact with Invokana:
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A total of 274 drugs are known to interact with Rybelsus:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 29, 2013 |
September 20, 2019 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Wegovy
Wegovy (semaglutide) an FDA-approved weekly injection for weight loss and to reduce heart risks ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Cozaar
Cozaar (losartan) is used to treat high blood pressure (hypertension). Includes Cozaar side ...
Avapro
Avapro (irbesartan) is used to treat high blood pressure and kidney problems caused by diabetes ...
Accupril
Accupril (quinapril) is used to treat high blood pressure (hypertension) and heart failure ...
Vasotec
Vasotec (enalapril) is used to treat high blood pressure, heart failure and kidney problems caused ...
Perindopril
Perindopril is used for coronary artery disease, diabetic kidney disease, heart attack, heart ...
Benazepril
Benazepril is used for diabetic kidney disease, heart failure, high blood pressure, left ...
Irbesartan
Irbesartan is used for diabetic kidney disease, high blood pressure
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.