Comparing Hydroxyzine vs Meclizine
| Hydroxyzine | Meclizine |
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| Hydroxyzine | Meclizine |
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Prescription only
Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more |
Prescription and OTC
Meclizine may be used to treat vertigo or nausea and vomiting associated with motion sickness; however, it takes approximately an hour to start working and may cause drowsiness, although it is less... View more |
Related suggestions |
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| More about Hydroxyzine | More about Meclizine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Hydroxyzine has an average rating of 5.9 out of 10 from a total of 1408 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
Meclizine has an average rating of 7.4 out of 10 from a total of 235 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Hydroxyzine side effects |
View all Meclizine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Hydroxyzine prices |
View all Meclizine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Vistaril | Antivert, Antrizine, Bonine, D-Vert, Dramamine All Day Less Drowsy, Dramamine II, Dramamine Less Drowsy, Driminate II, Help I'm Nauseous, Motion-Time, Sea-Calm, Travel Sickness, Travel-Ease View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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7 hours |
6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 581 drugs are known to interact with Hydroxyzine:
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A total of 286 drugs are known to interact with Meclizine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 12, 1956 |
February 14, 1957 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.