Meclizine Pregnancy and Breastfeeding Warnings

Brand names: Antivert, Antrizine, Bonine, D-Vert, Dramamine All Day Less Drowsy, Dramamine II, Dramamine Less Drowsy, Driminate II, Help I'm Nauseous, Meclicot, Medivert, Meni-D, Motion-Time, Ru-Vert-M, Sea-Calm, Travel Sickness, Travel-Ease, Verticalm

Medically reviewed by Drugs.com. Last updated on Aug 29, 2023.

Meclizine Pregnancy Warnings

This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: B

Animal studies have shown cleft palates at 25 to 50 times the human dose. However, epidemiological studies in pregnant women do not indicate this drug increases the risk of abnormalities when administered during pregnancy.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

See references

Meclizine Breastfeeding Warnings

Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: Large doses or more prolonged use may cause effects in the nursing infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established.

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in non-lactating women and in early postpartum women. However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment in postpartum mothers.

See references

Further information

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