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Meclizine Pregnancy and Breastfeeding Warnings

Meclizine is also known as: Antivert, Antrizine, Bonine, D-Vert, Dramamine All Day Less Drowsy, Dramamine II, Dramamine Less Drowsy, Driminate II, Help I'm Nauseous, Meclicot, Medivert, Meni-D, Motion-Time, Ru-Vert-M, Sea-Calm, Travel Sickness, Travel-Ease, Verticalm

Medically reviewed on December 12, 2017

Meclizine Pregnancy Warnings

Animal studies have shown cleft palates at 25 to 50 times the human dose. However, epidemiological studies in pregnant women do not indicate this drug increases the risk of abnormalities when administered during pregnancy.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: B

See references

Meclizine Breastfeeding Warnings

Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: Large doses or more prolonged use may cause effects in the nursing infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established.

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in non-lactating women and in early postpartum women. However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment in postpartum mothers.

See references

References for pregnancy information

  1. "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.

References for breastfeeding information

  1. "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
  2. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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