Meclizine Pregnancy and Breastfeeding Warnings
Medically reviewed by Drugs.com. Last updated on Jan 23, 2023.
Meclizine is also known as: Antivert, Antrizine, Bonine, D-Vert, Dramamine All Day Less Drowsy, Dramamine II, Dramamine Less Drowsy, Driminate II, Help I'm Nauseous, Meclicot, Medivert, Meni-D, Motion-Time, Ru-Vert-M, Sea-Calm, Travel Sickness, Travel-Ease, Verticalm
Meclizine Pregnancy Warnings
Animal studies have shown cleft palates at 25 to 50 times the human dose. However, epidemiological studies in pregnant women do not indicate this drug increases the risk of abnormalities when administered during pregnancy.
US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
This drug should be used during pregnancy only if clearly needed.
US FDA pregnancy category: B
Meclizine Breastfeeding Warnings
Caution is recommended.
Excreted into human milk: Unknown
Excreted into animal milk: Data not available
Comments: Large doses or more prolonged use may cause effects in the nursing infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established.
Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in non-lactating women and in early postpartum women. However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment in postpartum mothers.
See also
References for pregnancy information
- "Product Information. Antivert (meclizine)." Roerig Division (2001):
References for breastfeeding information
- "Product Information. Antivert (meclizine)." Roerig Division (2001):
- United States National Library of Medicine "Toxnet. Toxicology Data Network. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.