Comparing Estrace Vaginal Cream vs Premarin
| Estrace Vaginal Cream (estradiol) | Premarin (conjugated estrogens) |
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| Estrace Vaginal Cream (estradiol) | Premarin (conjugated estrogens) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Estrace Vaginal Cream may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Atrophic Vaginitis, Abnormal Uterine Bleeding, Atrophic Urethritis, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
Popular comparisons
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| More about Estrace Vaginal Cream (estradiol) | More about Premarin (conjugated estrogens) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Estrace Vaginal Cream has an average rating of 6.6 out of 10 from a total of 83 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 23% reported a negative effect. |
Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Estrace Vaginal Cream side effects |
View all Premarin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Lower cost generic approved | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Estrace Vaginal Cream prices |
View all Premarin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other estradiol brands include: Estring, Imvexxy, Vagifem, Yuvafem | Other conjugated estrogens brands include: Premarin Intravenous | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 260 drugs are known to interact with Estrace Vaginal Cream:
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A total of 357 drugs are known to interact with Premarin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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January 31, 1984 |
May 08, 1942 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.