Estrace Vaginal Cream and Pain: What Users Say

• His...
• November 15, 2015

For Atrophic Vaginitis "I was experiencing very painful intercourse with tearing. I have used this medication exactly 3 times. It has improved sex 99% already. Some pain on insertion, but none during intercourse for the first time in years! I have no doubt it will get better as my body's estrogen levels improve. So thankful. I am 55 years old."

• Anonymous
• July 14, 2009

For Atrophic Vaginitis "I'm a 41-year-old woman who went into early menopause two years ago. Vaginal dryness and all the other wonderful symptoms of menopause are not something that I would like to deal with at my age, but sometimes we can't control. So, my doctor prescribed Estrace, and I use 1mg 2x a week. I was told that it would take about 6-8 weeks before seeing a difference. At the end of that time frame, I saw only a slight difference in vaginal dryness but many side effects. I had headaches, dizziness, bloating, and calf pain."

• Pat...
• October 25, 2016

For Atrophic Vaginitis "This past February, I literally thought my insides were being ripped out. I expected to see them lying on the floor after sex one Monday afternoon. I was throbbing and hurting the rest of the evening and into the morning. The next day, I called my GYN and begged to be seen. She diagnosed me with this and several rips. She gave me an Estrace cream sample and a prescription along with one for the rips. I do not have medical insurance. I healed the rips with coconut oil and started the cream, 1 oz, 2 times a week. She says it is not absorbed. Well, all I know is that my hot flashes have lessened, sex is not painful, and if I don't use it like I'm supposed to, all that changes! I'm blessed to have friends in the medical field that can keep me supplied with samples."

• You...
• Taken for 1 to 6 months
• November 30, 2016

For Atrophic Vaginitis "I have suffered with endometriosis since I was 16 years of age. Needless to say, they did a full hysterectomy at 34 years of age, and I still suffered painful sex after having my hormone shots each month. I was still having pain. My doctor prescribed this cream, and so far, so good. Hopefully, it continues to help me. This is embarrassing to women, especially at this age."

• Cec...
• Taken for 1 to 6 months
• January 23, 2021

For Atrophic Vaginitis "My doctor prescribed a low dosage of Estrace Cream twice a week for frequent UTIs. Right off, I got severe itching but gave it time to go away, then got breast tenderness and pelvic pain. Been on it for almost 3 months. I haven't had a UTI, however, what side effects I have-not to mention the cost. Going to quit using it. I will figure a way to control the UTIs. Not worth dealing with the side effects."

• Ano...
• Taken for less than 1 month
• June 25, 2025

For Atrophic Vaginitis "I also am having extreme burning after applying only a pea-sized amount of the Estrace cream. The burning feels like a urinary tract infection, even though it's not. I use it only twice a week. I don't understand how such a small amount of the cream can cause so much burning and pain and inflammation. Dr. tells me to keep using it and the issues should subside, but I don't know. I am 69 years old and had a complete hysterectomy 25 years ago."

• Anonymous
• March 11, 2010

For Atrophic Vaginitis "I am 59, and it got to the point that I was avoiding sex. I had pain with intercourse and had to use lubricant all the time. I use 4mg once a week and am enjoying sex for the first time in years."