Estrace Vaginal Cream and Headaches: What Users Say

• InP...
• Taken for less than 1 month
• September 28, 2019

For Atrophic Vaginitis "I am 53 and had a complete hysterectomy 27 years ago and have been taking oral Premarin. Dr. Put me on the Estradiol patch which gave me headaches, so we just stopped all HRT. A few weeks later, I developed a UTI and had extreme vaginal and urethra pain. I was put on Estradiol Cream which irritated all of my skin, so they switched me to Estradiol vaginal tablets. I have been using it for 10 days and I am burning, aching, and it feels like something is stuck in me. I do not like this cream and am wondering if the Premarin cream would work better. I keep wondering if this pain will ever go away. Has anyone had symptoms for over 10 days while using the cream?"

• Anonymous
• July 14, 2009

For Atrophic Vaginitis "I'm a 41-year-old woman who went into early menopause two years ago. Vaginal dryness and all the other wonderful symptoms of menopause are not something that I would like to deal with at my age, but sometimes we can't control. So, my doctor prescribed Estrace, and I use 1mg 2x a week. I was told that it would take about 6-8 weeks before seeing a difference. At the end of that time frame, I saw only a slight difference in vaginal dryness but many side effects. I had headaches, dizziness, bloating, and calf pain."

• Not...
• October 7, 2015

For Atrophic Vaginitis "I have been using 1 mg every night for 12 days and am not sure if I can tolerate my side effect symptoms much longer to see if the cream actually works to diminish extremely painful intercourse due to dryness. I now have very tender breasts, a constant mild headache, and swelling, tenderness, and dryness of the external genitalia almost since the first day that I started using the cream. The only good effect so far is that my libido does seem to be heightened. So now I feel 'sexy' again but can't do anything about it because of all my discomfort! I plan on continuing to use the cream at every third day intervals for 2 more weeks to see if my side effects subside. If I am still miserable, I will stop the medication and look for a non-prescription vaginal moisturizer as my last hope for a continued sex life."

• Hys...
• September 27, 2017

For Atrophic Urethritis "Yesterday was the first time I used Estrace Vaginal Cream. I have experienced burning and throbbing. I will not use it again. My co-pay was $146.73. Wish there would have been samples. I could have saved the money."