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Estrace Vaginal Cream and Sore Breasts: What Users Say

Sore breasts: mentioned by 3 users (3.7%)

Based on user experiences from 82 Estrace Vaginal Cream reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 22.0%
itching 8.5%
dryness 7.3%
pain 7.3%
bleeding 4.9%
headaches 4.9%
sexual dysfunction 4.9%
swelling 4.9%
hot flashes 3.7%
sore breasts 3.7%

Reviews for Estrace Vaginal Cream

  • Not...
  • October 7, 2015

For Atrophic Vaginitis "I have been using 1 mg every night for 12 days and am not sure if I can tolerate my side effect symptoms much longer to see if the cream actually works to diminish extremely painful intercourse due to dryness. I now have very tender breasts, a constant mild headache, and swelling, tenderness, and dryness of the external genitalia almost since the first day that I started using the cream. The only good effect so far is that my libido does seem to be heightened. So now I feel 'sexy' again but can't do anything about it because of all my discomfort! I plan on continuing to use the cream at every third day intervals for 2 more weeks to see if my side effects subside. If I am still miserable, I will stop the medication and look for a non-prescription vaginal moisturizer as my last hope for a continued sex life."

5 / 10
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59 Report
  • Cra...
  • Taken for 1 to 6 months
  • October 25, 2017

For Atrophic Vaginitis "I had a hysterectomy 10 years ago and having a dryness problem, so the doctor prescribed this. After using this for about 6 weeks, I started cramping like I was beginning to start my period again, and my breasts were hurting so bad, just like the old days! I called my doctor and was taken off of it immediately due to previous breast cancer, and she said the estrogen from it gets into the bloodstream."

1 / 10
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27 Report
  • Cec...
  • Taken for 1 to 6 months
  • January 23, 2021

For Atrophic Vaginitis "My doctor prescribed a low dosage of Estrace Cream twice a week for frequent UTIs. Right off, I got severe itching but gave it time to go away, then got breast tenderness and pelvic pain. Been on it for almost 3 months. I haven't had a UTI, however, what side effects I have-not to mention the cost. Going to quit using it. I will figure a way to control the UTIs. Not worth dealing with the side effects."

5 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.