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Estrace Vaginal Cream and Bleeding: What Users Say

Bleeding: mentioned by 4 users (4.9%)

Based on user experiences from 82 Estrace Vaginal Cream reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 22.0%
itching 8.5%
dryness 7.3%
pain 7.3%
bleeding 4.9%
headaches 4.9%
sexual dysfunction 4.9%
swelling 4.9%
hot flashes 3.7%
sore breasts 3.7%

Reviews for Estrace Vaginal Cream

Commonly mentioned side effects
  • Sha...
  • December 20, 2015

For Atrophic Vaginitis "Used as directed and not sure it did much, truthfully. I have been having bioidentical estrogen and testosterone implants, and that does seem to be very effective. Also, an OTC product called Luvena (Restorative Vaginal Moisturizer, pH balanced) is super effective and doesn't cause the stinging and breakthrough bleeding of Estrace. Luvena is significantly cheaper than the insanely overpriced Estrace ($300 or a $72 co-pay). Really, Estrace should cost about $15 and not the criminally high price it is. Bottom line: Not a fan of Estrace and certainly not worth the $72 co-pay for stinging and bleeding for me at ten years post-menopause."

5 / 10
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  • Sha...
  • Taken for 1 to 2 years
  • December 23, 2015

For Atrophic Vaginitis "Side effects of breakthrough bleeding and little relief from thin tissue do not warrant the cost. If over $300 with a co-pay of $75. This is price gouging for a cream that should cost no more than $20 at the very most -- and I'm being generous. Overpriced meds are out of control. I won't bother using Estrace anymore."

4 / 10
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76 Report
  • She...
  • August 9, 2015

For Atrophic Vaginitis "I have been using Estrace vaginal cream for 8 weeks now, about 2x a week, and it has helped my vaginal dryness and prolapse, but I am experiencing side effects: anxiety, bleeding gums, joint and muscle pain, problems with sleep. I don't like this. I am going to look for a more natural estrogen."

5 / 10
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59 Report

See also:

Frequently asked questions

  • Che...
  • Taken for less than 1 month
  • August 16, 2016

For Atrophic Urethritis "I started using Estrace because of frequent urination with burning and dryness. I started menopause 4 yrs ago. When I use Estrace after 2 days, I have to stop due to bleeding and cramping that lasts for a week. I'm not a fan!"

4 / 10
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33 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.