Comparing Duloxetine vs Milnacipran
| Duloxetine | Milnacipran |
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| Duloxetine | Milnacipran |
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Prescription only
Duloxetine has antidepressant, anti-anxiety, and pain-relieving properties; however, it may cause a discontinuation syndrome on withdrawal even when tapered. Symptoms may include anxiety, headache... View more |
Prescription only
Prescribed for Fibromyalgia, Somatoform Pain Disorder, Reflex Sympathetic Dystrophy Syndrome. Milnacipran may also be used for purposes not listed in this medication guide. |
Related suggestions Fibromyalgia
Somatoform Pain Disorder
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| More about Duloxetine | More about Milnacipran | ||||||||
| Ratings & Reviews | |||||||||
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Duloxetine has an average rating of 6.2 out of 10 from a total of 2468 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Milnacipran has an average rating of 6.7 out of 10 from a total of 362 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Duloxetine side effects |
View all Milnacipran side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
View all Duloxetine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Cymbalta, Drizalma Sprinkle, Irenka | Savella | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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17 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 634 drugs are known to interact with Duloxetine:
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A total of 385 drugs are known to interact with Milnacipran:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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August 03, 2004 |
January 14, 2009 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.