Comparing Doxylamine vs Trazodone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Doxylamine	Trazodone	Enter another drug to compare

Doxylamine

Trazodone

Prescription and OTC

Prescribed for Insomnia, Allergic Rhinitis, Allergies, Conjunctivitis - Allergic, Nasal Congestion, Rhinorrhea, Upper Respiratory Tract Infection. Doxylamine may also be used for purposes not listed... View more

Prescription only

Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more

More about Doxylamine

More about Trazodone

Ratings & Reviews

Doxylamine has an average rating of 6.5 out of 10 from a total of 236 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 29% reported a negative effect.

Trazodone has an average rating of 6.3 out of 10 from a total of 1435 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect.

View all 236 reviews

View all 1435 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Drowsiness (24.6%)
Anxiety (5.5%)
Dizziness (5.5%)
Headaches (5.1%)
Tiredness (4.7%)
Dry mouth (3.8%)
Nausea (3.0%)

View all Doxylamine side effects

Drowsiness (17.7%)
Headaches (9.5%)
Dizziness (8.6%)
Anxiety (5.9%)
Dry mouth (5.7%)
Tiredness (4.9%)
Insomnia (4.6%)

View all Trazodone side effects

Drug Class

Miscellaneous anxiolytics, sedatives and hypnotics

Phenylpiperazine antidepressants

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	16 tablet
Strength	25 mg
Per unit^*	$0.66
Cost^*	$10.48

View all Doxylamine prices

Quantity	100 each
Strength	50 mg
Per unit^*	$0.20 - $0.21
Cost^*	$20.37 - $20.92

View all Trazodone prices

Get free Discount Card

Dosage Forms

Oral tablet

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

N/A

7.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 319 drugs are known to interact with Doxylamine:

19 major drug interactions (103 brand and generic names)
298 moderate drug interactions (1337 brand and generic names)
2 minor drug interactions (8 brand and generic names)

A total of 674 drugs are known to interact with Trazodone:

138 major drug interactions (504 brand and generic names)
521 moderate drug interactions (2174 brand and generic names)
15 minor drug interactions (71 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness... View more

Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness... View more

Disease Interactions

First Approval Date

April 07, 1948

December 24, 1981

WADA Class View classifications

N/A

More Information

Patient Resources

Doxylamine uses

Trazodone uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Doxylamine vs Trazodone

See also:

Augmentin

Zyrtec

Talvey

Ativan

Benadryl

Flonase

Bactrim

Claritin

Singulair

Ambien

Further information

Comparing Doxylamine vs Trazodone

See also:

Further information

Compare Drugs