Comparing Diphenhydramine vs Lorazepam
| Diphenhydramine | Lorazepam |
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| Diphenhydramine | Lorazepam |
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Prescription and OTC
Diphenhydramine is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and relieve some symptoms of Parkinson's disease. Sedation is a common side... View more |
Prescription only
Lorazepam may be used for the treatment of anxiety or as a preoperative medicine. It is potentially addictive and a withdrawal syndrome may be experienced upon discontinuation. Sedation is a common... View more |
Related suggestions Insomnia
Nausea/Vomiting
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| More about Diphenhydramine | More about Lorazepam | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Diphenhydramine has an average rating of 5.5 out of 10 from a total of 543 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 40% reported a negative effect. |
Lorazepam has an average rating of 7.9 out of 10 from a total of 1059 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Diphenhydramine side effects |
View all Lorazepam side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Diphenhydramine prices |
View all Lorazepam prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Aurodryl Children's Allergy, Banaril, Banophen, Beldin, Belix, Ben-Tann, Benadryl, Benadryl Allergy, Benadryl Children's Allergy, Benahist-10, Benahist-50, Benoject-50, Buckley's Bedtime, Bydramine, Calm-Aid, Complete Allergy Relief, Compoz Nighttime Sleep Aid, ConRx Allergy, Dicopanol, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Dormin, DPH, Dytan, Dytuss, Genahist, Help I Can't Sleep, Histaprin, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hyrexin, Miles Nervine, Nytol, Nytol Caplet, Nytol QuickCaps, Pharbedryl, Scot-Tussin Allergy, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep Tab II, Sleep Tablets, Sleep-ettes D, Sleepinal, Sleepwell 2-nite, Snooze Fast, Sominex, Sominex Maximum Strength Caplet, Trux-adryl, Twilite, Unisom Liquid, Unisom SleepGels, Unisom SleepMelts, Unisom SleepMinis, Valu-Dryl, Vanamine PD, Vicks QlearQuil Nighttime Allergy Relief, Z-Sleep, ZzzQuil View more | Ativan, Ativan Injection, Lorazepam Intensol, Loreev XR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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9.3 hours |
25 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 449 drugs are known to interact with Diphenhydramine:
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A total of 406 drugs are known to interact with Lorazepam:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 04, 1946 |
September 30, 1977 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.