Comparing Benadryl vs Diphenhydramine
Benadryldiphenhydramine |
Diphenhydramine |
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Benadryl is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, and as a sleep aid, and to relieve some symptoms of Parkinson's disease. Sedation is a common side... more |
Diphenhydramine is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and to relieve some symptoms of Parkinson's disease. Sedation is a common... more |
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Prescription and OTC |
Prescription and OTC |
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Ratings & ReviewsRecent helpful reviews |
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7.6
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7.0
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Drug Class |
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Side Effects |
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See the full Benadryl side effects document. |
See the full diphenhydramine side effects document. |
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Pricing and Coupons* Prices are without insurance |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Other diphenhydramine brands include: Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix,... more | Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix,... more | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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9.3 hours |
9.3 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 819 drugs are known to interact with Benadryl:
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A total of 819 drugs are known to interact with diphenhydramine:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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March 04, 1946 |
March 04, 1946 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Allergic Reactions I was given Benadryl at the hospital for an allergic reaction. It instantly shot my heart rate up to 217 bpm and instantly my mouth got dry I couldn't swallow my chest felt hot like an elephant was sitting on it and I got really cold. It put me into shock my body wouldn't stop shaking, I could breath. It was so scary I thought I was dead thanks to the doctors quick response he saved me but it almost killed me.