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Comparing Diphenhydramine

Diphenhydramine

Diphenhydramine is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and to relieve some symptoms of Parkinson's disease. Sedation is a common... more

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Insomnia
Nausea/Vomiting
Allergic Reactions
Allergic Rhinitis
Cough
Cold Symptoms
Extrapyramidal Reaction
Motion Sickness
Pruritus
Urticaria
Show more conditions...

Prescription and OTC

Ratings & Reviews

Recent helpful reviews
7.0
192 Reviews

For Insomnia Works quite well on insomnia but careful when combining with other meds that also work on your sympathetic/parasympathetic nervous system. I took it with lexapro and got significant problems with too low heart rate, respiratory issues and hypnic jerks.

7
avalokiteshwara

For Insomnia I take this to help me sleep every now and then, however the last 2 times I've been having weird and slightly creepy visual and auditory hallucinations, it's almost like I'm having an incredibly realistic dream while I'm completely conscious and full functionable! But other than that it knocks me right out

7
Bethanyb123

View all 192 reviews

Drug Class

Side Effects

See the full diphenhydramine side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 4 capsule
Dosage 25 mg
Per Unit* $1.09
Cost* $4.37
View all diphenhydramine prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available
  • Injectable solution
  • Oral capsule
  • Oral liquid
  • Oral tablet

Brand Names
Aler-Dryl, Aler-Tab, Aller-G-Time, Allergia-C, Allermax, Altaryl, Banaril, Banophen, Beldin, Belix,... more

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

9.3 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.

FDA Alerts

N/A

Drug Interactions

A total of 820 drugs are known to interact with diphenhydramine:

  • 33 major drug interactions (160 brand and generic names)
  • 783 moderate drug interactions (4678 brand and generic names)
  • 4 minor drug interactions (12 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Ask your doctor before using diphenhydrAMINE together with alcohol. Use alcohol cautiously. ... more

Disease Interactions

First Approval Date

March 04, 1946

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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