Comparing Cyclobenzaprine vs Guaifenesin
| Cyclobenzaprine | Guaifenesin |
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| Cyclobenzaprine | Guaifenesin |
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Prescription only
Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... View more |
Prescription and OTC
Guaifenesin is an expectorant that helps thin and remove mucus from the airways. It is generally well tolerated. Prescribed for Bronchitis, Bronchiectasis, Fibromyalgia, Cough. Guaifenesin may also... View more |
Related suggestions |
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| More about Cyclobenzaprine | More about Guaifenesin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Cyclobenzaprine has an average rating of 6.0 out of 10 from a total of 620 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 30% reported a negative effect. |
Guaifenesin has an average rating of 7.1 out of 10 from a total of 306 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 24% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Cyclobenzaprine side effects |
View all Guaifenesin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cyclobenzaprine prices |
View all Guaifenesin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Amrix, Comfort Pac with Cyclobenzaprine | Air Power, Allfen Jr, Altarussin, Altorant, Amibid LA, Anti-Tuss, Aquamist, Balminil Expectorant, Beechams Veno's Expectorant, Beechams Veno's for Kids Chesty Cough, Benadryl Chesty Forte, Benylin E, Bidex-400, Breonesin, Bronchoril, Buckley's Chest Congestion, Calmylin Expectorant, Diabetic Expectorant, Diabetic Tuss, Diabetic Tussin Chest Congestion, Diabetic Tussin Mucus Relief, Dristan Chesty Cough, Dristan Chesty Cough Guaiphenesin, Drituss G, Duratuss G, Family Meltus Chesty Coughs, Fenesin, Fenesin IR, Fenex-LA, G Bid, Ganidin NR, Genatuss, GG 200 NR, GG-Cen, Giltuss Children's EX Expectorant, Giltuss EX Expectorant, Glytuss, Gua-SR, Guaiatussin, Guaibid-LA, Guaifen NR, Guaifenesin LA, Guaifenex G, Guaifenex LA, Guiacough, Guiadrine G-1200, Guiatuss, Help I Have Chest Congestion, Hill's Balsam Chesty Cough, Humavent LA, Humibid, Humibid E, Humibid Pediatric, Humigen LA, Hytuss, Junior Meltus Chesty Coughs with Catarrh, Junior Meltus Colour and Sugar Free Expectorant, Lemsip Cough Chesty, Mucaplex, Mucinex, Mucinex Children's Chest Congestion, Mucinex for Kids, Mucinex Maximum Strength, Mucobid-LA, Organ-1 NR, Refenesen Chest Congestion Relief, Robafen, Robitussin Mucus + Chest Congestion, Rompe Pecho EX, Scot-Tussin Expectorant, Siltuss DAS, Siltussin DAS, Siltussin DAS-NA, TabTussin 400, Tussin Expectorant, Tussin Mucus + Chest Congestion, Xpect View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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72 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 452 drugs are known to interact with Cyclobenzaprine:
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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August 26, 1977 |
July 12, 2002 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.