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Guaifenesin and Diarrhea: What Users Say

Brand names: Mucinex, Mucinex Maximum Strength, Humibid, Breonesin, Tussin Expectorant, Robafen, Family Meltus Chesty Coughs, Fenesin, Guaiatussin, Organ-1 NR, Scot-Tussin Expectorant, Guiatuss, Altarussin, Diabetic Tuss, Guiadrine G-1200, Xpect, Junior Meltus Chesty Coughs with Catarrh, Dristan Chesty Cough Guaiphenesin, Benadryl Chesty Forte, G Bid, Ganidin NR, Humibid Pediatric, Mucinex Children's Chest Congestion, Guaibid-LA, Aquamist, Amibid LA, Mucobid-LA, Guaifenex LA, Fenex-LA, Rompe Pecho EX, Guaifenesin LA, Humavent LA, Guiacough, GG 200 NR, Glytuss, Anti-Tuss, Diabetic Expectorant, Allfen Jr, Genatuss, Siltuss DAS, Gua-SR, Humigen LA, Altorant, Duratuss G, Robitussin Mucus + Chest Congestion, Guaifenex G, GG-Cen, Benylin E Calmylin Expectorant Siltussin DAS-NA Balminil Expectorant Drituss G Beechams Veno's for Kids Chesty Cough Junior Meltus Colour and Sugar Free Expectorant Help I Have Chest Congestion Bidex-400 Humibid E Fenesin IR Hill's Balsam Chesty Cough Beechams Veno's Expectorant Lemsip Cough Chesty Dristan Chesty Cough Mucinex for Kids Guaifen NR Buckley's Chest Congestion TabTussin 400 Siltussin DAS Diabetic Tussin Mucus Relief Refenesen Chest Congestion Relief Bronchoril Hytuss Mucaplex Tussin Mucus + Chest Congestion Air Power Diabetic Tussin Chest Congestion Giltuss EX Expectorant Giltuss Children's EX Expectorant …show all brand names

Diarrhea: mentioned by 7 users (2.3%)

Based on user experiences from 306 Guaifenesin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 4.9%
nausea 4.9%
cough 3.9%
drowsiness 3.9%
pain 3.6%
vomiting 2.6%
diarrhea 2.3%
headaches 2.3%
insomnia 2.0%
upset stomach 2.0%

Reviews for Guaifenesin

Showing 7 reviews tagged with "diarrhea". Clear filters to view all 306 reviews.
Commonly mentioned side effects
  • Anonymous
  • November 7, 2011

Guaifenesin for Cough "About an hour and a half after taking one Mucinex DM, I developed severe dizziness, drowsiness, bad intestinal cramps, vomiting, and diarrhea that recurred over a period of 2 hours. It was the only medication in my system."

1 / 10
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  • Con...
  • December 23, 2016

Guaifenesin for Cough "The doctor gave me a sample of this when I complained of congestion. I took two tablets, which may have been too much since I developed the runs. I'll try it again, but only one tablet. Or, I may just get Robitussin since the doctor said that Mucinex is a magnified version of Robitussin."

5 / 10
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  • Cha...
  • Taken for less than 1 month
  • August 31, 2018

For Cough "I used guaifenesin for mucus relief with a cough. I drank a full bottle of water with it and 30 minutes later, ate supper. At 12:30, I woke up with vomiting and severe diarrhea. Blood pressure went sky high (from a normal low). Headache and dizziness. I couldn’t eat for 2 1/2 days because of the nausea. Blood pressure went back to normal after 24 hours. I have used other cold medicines, and every one would make me at least slightly nauseous. I didn’t know they all contained this ingredient. This seems to be abnormal for this medicine, so I think I may be allergic."

1 / 10
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Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • January 6, 2025

Guaifenesin for Cough "I highly recommend drinking large amounts of water with this medication. I was not aware to do so because it was nowhere to be found on the label, and it resulted in vomiting and the runs. After hours of this and speaking with a nurse, I was able to get it under control. Will not ever take again."

3 / 10
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  • Anonymous
  • October 20, 2014

Guaifenesin for Cough "I've been up for hours, throwing up and having diarrhea after taking this."

2 / 10
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  • Jo7...
  • January 15, 2017

Guaifenesin for Cough "Gave me diarrhea, dizziness, nausea, stomach cramps, and even some numbness in tongue/face. Worse than the cough. Never again."

1 / 10
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  • Tin...
  • September 7, 2021

Guaifenesin "I took Mucinex Cold & Flu, and it works, but it made me have diarrhea, severe stomach problems, and nausea."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.